DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rala and RALB

DIOPT Version :9

Sequence 1:	NP_525063.1	Gene:	Rala / 31332	FlyBaseID:	FBgn0015286	Length:	201	Species:	Drosophila melanogaster
Sequence 2:	NP_001356329.1	Gene:	RALB / 5899	HGNCID:	9840	Length:	206	Species:	Homo sapiens

Alignment Length:	194	Identity:	146/194 - (75%)
Similarity:	166/194 - (85%)	Gaps:	2/194 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 ALHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAA 74
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Human    13 ALHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAA 77

  Fly    75 IRDNYFRSGEGFLCVFSITDDESFQATQEFREQILRVKNDE-SIPFLLVGNKCDLNDKRKVPLSE 138
            |||||||||||||.|||||:.|||.||.||||||||||.:| .||.|:||||.||.::|:||:.|
Human    78 IRDNYFRSGEGFLLVFSITEHESFTATAEFREQILRVKAEEDKIPLLVVGNKSDLEERRQVPVEE 142

  Fly   139 CQLRAQQWAVPYVETSAKTRENVDKVFFDLMREIRSRKTEDSKATSGRAKDRCKKR-RLKCTLL 201
            .:.:|::|.|.|||||||||.||||||||||||||::|..::|..:|:...:.||. :.:|.||
Human   143 ARSKAEEWGVQYVETSAKTRANVDKVFFDLMREIRTKKMSENKDKNGKKSSKNKKSFKERCCLL 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rala	NP_525063.1	RalA_RalB	12..174	CDD:206710	135/162 (83%)
RALB	NP_001356329.1	RalA_RalB	15..178	CDD:206710	135/162 (83%)
		Effector region	43..51		7/7 (100%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	180..206		6/25 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	279	1.000	Domainoid score	I1704
eggNOG	1	0.900	-	-		E2759_KOG0395
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	304	1.000	Inparanoid score	I2662
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1259506at2759
OrthoFinder	1	1.000	-	-		FOG0002545
OrthoInspector	1	1.000	-	-		otm41018
orthoMCL	1	0.900	-	-		OOG6_104721
Panther	1	1.100	-	-	O	PTHR24070
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1669
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	12	11.830