DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rala and Rras

DIOPT Version :9

Sequence 1:	NP_525063.1	Gene:	Rala / 31332	FlyBaseID:	FBgn0015286	Length:	201	Species:	Drosophila melanogaster
Sequence 2:	NP_001101951.1	Gene:	Rras / 361568	RGDID:	1311443	Length:	218	Species:	Rattus norvegicus

Alignment Length:	203	Identity:	92/203 - (45%)
Similarity:	125/203 - (61%)	Gaps:	10/203 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KKPTAGPALHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTA 67
            :.|..|.. ||:::||.|||||||||:||:...||.||:||..|||.|...:||...::||||||
  Rat    22 RDPPPGET-HKLVVVGGGGVGKSALTIQFIQSYFVSDYDPTIEDSYTKICTVDGIPARLDILDTA 85

  Fly    68 GQEDYAAIRDNYFRSGEGFLCVFSITDDESFQATQEFREQILRVKNDESIPFLLVGNKCDLNDKR 132
            |||::.|:|:.|.|:|.|||.||:|.|.:||....:...||||||:.:..|.:|||||.||..:|
  Rat    86 GQEEFGAMREQYMRAGNGFLLVFAINDRQSFIEVSKLFTQILRVKDRDDFPIVLVGNKADLETQR 150

  Fly   133 KVPLSECQLRAQQWAVPYVETSAKTRENVDKVFFDLMREIRSRKTED---SKATSGRAKD-RCKK 193
            :|..||....:....:.|.|.|||.|.|||:.|..|:|.:|..:.::   |..::.|.|| ||
  Rat   151 QVLRSEASSFSASHHMTYFEASAKLRLNVDEAFEQLVRTVRKYQEQELPPSPPSAPRKKDGRC-- 213

  Fly   194 RRLKCTLL 201
               .|.||
  Rat   214 ---PCVLL 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rala	NP_525063.1	RalA_RalB	12..174	CDD:206710	80/161 (50%)
Rras	NP_001101951.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..30		2/8 (25%)
		P-loop_NTPase	28..191	CDD:304359	80/163 (49%)
		small_GTPase	42..193	CDD:197466	73/150 (49%)
		Effector region	58..66		4/7 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0395
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1259506at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820