Protein Alignment Rala and ERAS

DIOPT Version :10

• Sequence 1: NP_525063.1
• Gene: Rala / 31332
• FlyBaseID: FBgn0015286
• Length: 201
• Species: Drosophila melanogaster
• Sequence 2: NP_853510.1
• Gene: ERAS / 3266
• HGNCID: 5174
• Length: 233
• Species: Homo sapiens
• Alignment Length: 191
• Identity: 73/191 - (38%)
• Similarity: 104/191 - (54%)
• Gaps: 8/191 - (4%)

  Fly    12 HKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAAIR 76
            :|.::||:.||||||||:|..:..||||::||..|||.|::.||..:..:::||||||..:.|:|
Human    42 YKAVVVGASGVGKSALTIQLNHQCFVEDHDPTIQDSYWKELTLDSGDCILNVLDTAGQAIHRALR 106

  Fly    77 DNYFRSGEGFLCVFSITDDESFQATQEFREQILRVKNDE-SIPFLLVGNKCDLNDKRKVPLSECQ 140
            |......:|.|.||::.|..|....|    ||....... :.|.:||||||||........:...
Human   107 DQCLAVCDGVLGVFALDDPSSLIQLQ----QIWATWGPHPAQPLVLVGNKCDLVTTAGDAHAAAA 167

  Fly   141 LRAQQWAVPYVETSAKTRENVDKVFFDLMREI---RSRKTEDSKATSGRAKDRCKKRRLKC 198
            ..|..|...:||||||||:.|::.|..|:.||   :....::..|.|.|.|.|.:|....|
Human   168 ALAHSWGAHFVETSAKTRQGVEEAFSLLVHEIQRVQEAMAKEPMARSCREKTRHQKATCHC 228

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rala	NP_525063.1	RalA_RalB	12..174	CDD:206710	66/165 (40%)
ERAS	NP_853510.1	RalA_RalB	42..201	CDD:206710	66/162 (41%)
		Effector region	70..78		3/7 (43%)