DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rala and Nras

DIOPT Version :9

Sequence 1:	NP_525063.1	Gene:	Rala / 31332	FlyBaseID:	FBgn0015286	Length:	201	Species:	Drosophila melanogaster
Sequence 2:	NP_542944.1	Gene:	Nras / 24605	RGDID:	3205	Length:	189	Species:	Rattus norvegicus

Alignment Length:	178	Identity:	92/178 - (51%)
Similarity:	130/178 - (73%)	Gaps:	5/178 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 HKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAAIR 76
            :|:::||:|||||||||:|.:.:.||::|:||..|||||:||:|||...:|||||||||:|:|:|
  Rat     4 YKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMR 68

  Fly    77 DNYFRSGEGFLCVFSITDDESFQATQEFREQILRVKNDESIPFLLVGNKCDLNDKRKVPLSECQL 141
            |.|.|:||||||||:|.:.:||.....:||||.|||:.:.:|.:|||||||| ..|.|...:...
  Rat    69 DQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDL-PTRTVDTKQAHE 132

  Fly   142 RAQQWAVPYVETSAKTRENVDKVFFDLMREIRS---RKTEDSK-ATSG 185
            .|:.:.:|::|||||||:.|:..|:.|:||||.   :|...|: .|.|
  Rat   133 LAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQYRMKKLNSSEDGTQG 180

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rala	NP_525063.1	RalA_RalB	12..174	CDD:206710	87/161 (54%)
Nras	NP_542944.1	H_N_K_Ras_like	3..164	CDD:133338	86/160 (54%)
		Effector region	32..40		4/7 (57%)
		Hypervariable region. /evidence=ECO:0000250	166..185		4/15 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0395
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1259506at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820