DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Rala and RRAS2

DIOPT Version :9

Sequence 1:NP_525063.1 Gene:Rala / 31332 FlyBaseID:FBgn0015286 Length:201 Species:Drosophila melanogaster
Sequence 2:NP_036382.2 Gene:RRAS2 / 22800 HGNCID:17271 Length:204 Species:Homo sapiens


Alignment Length:188 Identity:90/188 - (47%)
Similarity:126/188 - (67%) Gaps:13/188 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 AGPALHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQED 71
            :|...:::::||.|||||||||:||:...||.||:||..|||.|:.|:|....::|||||||||:
Human    10 SGQEKYRLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDRAARLDILDTAGQEE 74

  Fly    72 YAAIRDNYFRSGEGFLCVFSITDDESFQATQEFREQILRVKNDESIPFLLVGNKCDLNDKRKVPL 136
            :.|:|:.|.|:|||||.|||:||..||:...:|:.||||||:.:..|.:|:|||.||:.:|:|..
Human    75 FGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQ 139

  Fly   137 SECQLRAQQWAVPYVETSAKTRENVDKVFFDLMREIR-------------SRKTEDSK 181
            .|.|..|:|..|.|:|.|||.|.|||:.|.:|:|.||             :||.:|.|
Human   140 EEGQQLARQLKVTYMEASAKIRMNVDQAFHELVRVIRKFQEQECPPSPEPTRKEKDKK 197

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RalaNP_525063.1 RalA_RalB 12..174 CDD:206710 85/174 (49%)
RRAS2NP_036382.2 M_R_Ras_like 13..176 CDD:133345 83/162 (51%)
Effector region 43..51 4/7 (57%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0395
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1259506at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.820

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