Protein Alignment Rala and DIRAS1

DIOPT Version :10

• Sequence 1: NP_525063.1
• Gene: Rala / 31332
• FlyBaseID: FBgn0015286
• Length: 201
• Species: Drosophila melanogaster
• Sequence 2: XP_047294230.1
• Gene: DIRAS1 / 148252
• HGNCID: 19127
• Length: 232
• Species: Homo sapiens
• Alignment Length: 211
• Identity: 75/211 - (35%)
• Similarity: 115/211 - (54%)
• Gaps: 18/211 - (8%)

  Fly     3 KKPTAGPAL-----HKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQID 62
            :.|.||...     ::|::.|:||||||:|.|:|:...|.:.|.||..|:||:.:..|.....:.
Human    28 RPPAAGKMPEQSNDYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTIEDTYRQVISCDKSVCTLQ 92

  Fly    63 ILDTAGQEDYAAIRDNYFRSGEGFLCVFSITDDESFQATQEFREQILRVKND-ESIPFLLVGNKC 126
            |.||.|...:.|::......|..|:.|||:|..:|.:......:.|:::|.. |.||.:||||||
Human    93 ITDTTGSHQFPAMQRLSISKGHAFILVFSVTSKQSLEELGPIYKLIVQIKGSVEDIPVMLVGNKC 157

  Fly   127 DLNDKRKVPLSECQLRAQQWAVPYVETSAKTRENVDKVFFDLMREIRSRKTE----DSKATSGRA 187
            | ..:|:|...|.|..||:|...::|||||...||.::|.:|: .:.:|:..    |.| .||:.
Human   158 D-ETQREVDTREAQAVAQEWKCAFMETSAKMNYNVKELFQELL-TLETRRNMSLNIDGK-RSGKQ 219

  Fly   188 K--DRCKKRRLKCTLL 201
            |  ||.|.   ||||:
Human   220 KRTDRVKG---KCTLM 232

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rala	NP_525063.1	RalA_RalB	12..174	CDD:206710	59/162 (36%)
DIRAS1	XP_047294230.1	P-loop containing Nucleoside Triphosphate Hydrolases	41..202	CDD:476819	59/162 (36%)