DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rala and Rgk1

DIOPT Version :9

Sequence 1:	NP_525063.1	Gene:	Rala / 31332	FlyBaseID:	FBgn0015286	Length:	201	Species:	Drosophila melanogaster
Sequence 2:	NP_725875.3	Gene:	Rgk1 / 14462605	FlyBaseID:	FBgn0264753	Length:	1379	Species:	Drosophila melanogaster

Alignment Length:	208	Identity:	60/208 - (28%)
Similarity:	97/208 - (46%)	Gaps:	29/208 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SKKPTAGPALHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKK---VVLDGEEVQIDI 63
            :..|..||  ::|:|:|...||||:|..|||..|::..|:.:..|...:|   |:|.|||.::..
  Fly  1113 TSNPGNGP--YRVLMLGGPAVGKSSLVSQFMTSEYLHAYDTSIDDESGEKAVSVLLSGEESELIF 1175

  Fly    64 LDTAGQEDYAAIR-----DNYFRSGEGFLCVFSITDDESFQATQEFREQILRV----KNDESIPF 119
            :|    ..|..:.     .||  ...|:..::|..|..||...    ||:|:|    :|......
  Fly  1176 ID----HGYTEMTPDECLTNY--DPHGYCVIYSAADRSSFSVA----EQVLQVLWTNQNIAQKAV 1230

  Fly   120 LLVGNKCDLNDKRKVPLSECQLRAQQWAVPYVETSAKTRENVDKVFFDLMREIRSRKTEDSKATS 184
            :||.||.||...|.|...|.:..|..:...::|||.....|||::...|:.:||.:.....|
  Fly  1231 ILVSNKADLARSRLVTSEEGKAMATAYDCKFIETSVGINHNVDELLVGLLSQIRLKLENPEK--- 1292

  Fly   185 GRAKDRCKKRRLK 197
              ::|..:||.::
  Fly  1293 --SRDLFRKRSIR 1303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rala	NP_525063.1	RalA_RalB	12..174	CDD:206710	52/173 (30%)
Rgk1	NP_725875.3	DUF2967	459..715	CDD:288079
		P-loop_NTPase	1121..1379	CDD:304359	57/198 (29%)
		small_GTPase	1121..1286	CDD:197466	53/174 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910