Protein Alignment Mnt and ARNT2

DIOPT Version :9

• Sequence 1: NP_001162651.1
• Gene: Mnt / 31331
• FlyBaseID: FBgn0023215
• Length: 790
• Species: Drosophila melanogaster
• Sequence 2: NP_055677.3
• Gene: ARNT2 / 9915
• HGNCID: 16876
• Length: 717
• Species: Homo sapiens
• Alignment Length: 687
• Identity: 128/687 - (18%)
• Similarity: 222/687 - (32%)
• Gaps: 212/687 - (30%)

  Fly   143 EGRPHVSEDDNSSINNNNNNNNTHPPQQQQHSAAGRTTTTRITTTPAILTKLMGNSVTPASNTTS 207
            ||....|.:::|.|.....|..|.                       .:|:|  :.:.|
Human    58 EGPSKFSRENHSEIERRRRNKMTQ-----------------------YITEL--SDMVP------ 91

  Fly   208 LPTSTPSVTTSPPASTDFMLLAAAATSATSATPATATSAAATAASNPAKRKLSSIAEIPSKFLVV 272
                |.|.....|.....:.:|.:...:...|...:|..|         .|.|.:.|...|.|::
Human    92 ----TCSALARKPDKLTILRMAVSHMKSMRGTGNKSTDGA---------YKPSFLTEQELKHLIL 143

  Fly   273 SDAKG---VYSAHTHPNGFAADSLGVDNNETMIKKLMQNLQSQRQQQSLQQLR-SLRPAEISLTP 333
            ..|.|   |.:|.|....:.:||:....|:...:.....|..|.....:::|| .|..:|.|:|
Human   144 EAADGFLFVVAAETGRVIYVSDSVTPVLNQPQSEWFGSTLYEQVHPDDVEKLREQLCTSENSMT- 207

  Fly   334 PPAATRKVDISNSRTRSYSLSNVSAARDQQDHPQHQQHANHMQIQQHYGYM-------------- 384
                .|.:|:.....:.                :.||.:..|.:.....::
Human   208 ----GRILDLKTGTVKK----------------EGQQSSMRMCMGSRRSFICRMRCGNAPLDHLP 252

  Fly   385 -----------RSNIGGVIYGLHKDSADSAASSACGAGAGAAAVGMSIASSAPAAGSQLSAHHHT 438
                       |:.:|.|..|    .|..|.....|........||:|    |...:.:
Human   253 LNRITTMRKRFRNGLGPVKEG----EAQYAVVHCTGYIKAWPPAGMTI----PEEDADV------ 303

  Fly   439 GHG--------GRRRTTSS-------------------NSNGAGT-------------------R 457
            |.|        ||.:.|||                   ||:|..|                   :
Human   304 GQGSKYCLVAIGRLQVTSSPVCMDMNGMSVPTEFLSRHNSDGIITFVDPRCISVIGYQPQDLLGK 368

  Fly   458 EVHNKLEKERRAQLKECYDLLKK----VLPMGDEDRKKTSNLTILDTA-----HKYVNSLSHEVC 513
            ::......|.::.|:|.:..:.|    ||.:....|.|.....::.|:     :.|.:.:.:.:|
Human   369 DILEFCHPEDQSHLRESFQQVVKLKGQVLSVMYRFRTKNREWMLIRTSSFTFQNPYSDEIEYIIC 433

  Fly   514 EQEAKIEKLAKQKIELQKR----LKQLSLRRESPPTDQQIIPQADKAV--CLATTATTAPPTAAS 572
             ....:::|.:|:.||:..    |....|.:...|.....:.:|.|:|  ..|..:....|..|.
Human   434 -TNTNVKQLQQQQAELEVHQRDGLSSYDLSQVPVPNLPAGVHEAGKSVEKADAIFSQERDPRFAE 497

  Fly   573 GHNGTTI----LFDAGNACATGQLTTVINKTNGGATAAASSKHNGNHTGGA-TTTLTPAMGIMTI 632
            ...|.:.    :..:.:|..|.|:            .:..|.....|:|.| ::::....|:..|
Human   498 MFAGISASEKKMMSSASAAGTQQI------------YSQGSPFPSGHSGKAFSSSVVHVPGVNDI 550

  Fly   633 KNGNGSNGNMLAISPTGGHNHQLHQHHNGSPAGSPSGIGATTGATITRGSPTPSTPSPSPS---- 693
            ::.:.:..||..||      .||:|..           .|.||:.    .|.|....||.|
Human   551 QSSSSTGQNMSQIS------RQLNQSQ-----------VAWTGSR----PPFPGQQIPSQSSKTQ 594

  Fly   694 SSSSGVSLSTSFMGGSSSSSSSSSSSSSSSSSSSSSS 730
            ||..|:..|.::....||.|..||.::||.|.::.||
Human   595 SSPFGIGTSHTYPADPSSYSPLSSPATSSPSGNAYSS 631

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mnt	NP_001162651.1	HLH	457..512	CDD:238036	10/63 (16%)
ARNT2	NP_055677.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	35..74		5/15 (33%)
		bHLH-PAS_ARNT	62..124	CDD:381517	13/96 (14%)
		PAS	137..243	CDD:395786	23/126 (18%)
		PAS_11	336..436	CDD:405306	15/100 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	548..717		30/105 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910