DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mnt and MLX

DIOPT Version :9

Sequence 1:	NP_001162651.1	Gene:	Mnt / 31331	FlyBaseID:	FBgn0023215	Length:	790	Species:	Drosophila melanogaster
Sequence 2:	NP_733752.1	Gene:	MLX / 6945	HGNCID:	11645	Length:	298	Species:	Homo sapiens

Alignment Length:	189	Identity:	43/189 - (22%)
Similarity:	72/189 - (38%)	Gaps:	33/189 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   349 RSYSLSNVSAARDQQDHPQHQQHANHMQIQQHYGYMRSNI--GGVIYGLHKDSADSAASSACGAG 411
            :|.:||.....|:...||        ...:..|.|..:::  |..:....|.|..|.|:|
Human    47 KSPTLSVPRGCREDSSHP--------ACAKVEYAYSDNSLDPGLFVESTRKGSVVSRANS----- 98

  Fly   412 AGAAAVGMSIASSAPAAGSQLSAHHHTGHGGRRRTTSSNSNGAGTREVHNKLEKERRAQLKECYD 476
                 :|.:.|||.|....:.|.:|...:        ..|.....|..|.:.|::||..:|..||
Human    99 -----IGSTSASSVPNTDDEDSDYHQEAY--------KESYKDRRRRAHTQAEQKRRDAIKRGYD 150

  Fly   477 LLKKVLPMGDED-----RKKTSNLTILDTAHKYVNSLSHEVCEQEAKIEKLAKQKIELQ 530
            .|:.::|...:.     .:|.|...:|.....|:..|..|..:||.::..|.|....|:
Human   151 DLQTIVPTCQQQDFSIGSQKLSKAIVLQKTIDYIQFLHKEKKKQEEEVSTLRKDVTALK 209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mnt	NP_001162651.1	HLH	457..512	CDD:238036	15/59 (25%)
MLX	NP_733752.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..63		4/15 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	91..145		17/71 (24%)
		HLH	130..188	CDD:306515	14/57 (25%)
		Leucine-zipper	140..160		7/19 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910