Protein Alignment Mnt and Mnt

DIOPT Version :9

• Sequence 1: NP_001162651.1
• Gene: Mnt / 31331
• FlyBaseID: FBgn0023215
• Length: 790
• Species: Drosophila melanogaster
• Sequence 2: NP_034943.3
• Gene: Mnt / 17428
• MGIID: 109150
• Length: 591
• Species: Mus musculus
• Alignment Length: 589
• Identity: 140/589 - (23%)
• Similarity: 187/589 - (31%)
• Gaps: 220/589 - (37%)

  Fly   187 TPAILTKLMGNSVTPASNTTSLPTSTPSVTTSPPASTDFMLLAAAATSATSATPATATSAAATAA 251
            |||.||      |.|....|:.|.|.|.....|||:....|  |....|..:||..:.....|..
Mouse    84 TPAPLT------VIPIPVVTNSPQSLPPPPPLPPAAQPLPL--APRQPALVSTPGLSIKEPVTLP 140

  Fly   252 SNPAKRKLSSIAEIPSKFLVVSDAKGVYSAHTHPNGFAADSLGVDNNETMIKKLMQNLQSQRQQQ 316
            :.|         ::|:...::.|||...:    |.|                          ..:
Mouse   141 TRP---------QVPTPAPLLPDAKTTVA----PTG--------------------------SPK 166

  Fly   317 SLQQLRSLRPAEI-SLTPPPAATRKVDISNSRTRSYSLSNVSAARDQQDHPQHQQHANHMQIQQH 380
            .||.|    ||.| ::.|.|....::                  ..||..|.
Mouse   167 PLQPL----PAPILTIAPHPGVQPQL------------------APQQPPPP------------- 196

  Fly   381 YGYMRSNIGGVIYGLHKDSADSAASSACGAGAGAAAVGMSIASSAPAAGSQLSAHHHTGHGGRRR 445
                                                 .:.....|||..::.|..
Mouse   197 -------------------------------------TLGTLKLAPAEEAKSSEQ---------- 214

  Fly   446 TTSSNSNGAGTREVHNKLEKERRAQLKECYDLLKKVLPMGDEDRKKTSNLTILDTAHKYVNSLSH 510
              .....|.|||||||||||.|||.||||::.||:.:|  :.|.||||||::|.||.:|:.||..
Mouse   215 --KKRPGGIGTREVHNKLEKNRRAHLKECFETLKRNIP--NVDDKKTSNLSVLRTALRYIQSLKR 275

  Fly   511 EVCEQEAKIEKLAKQKIELQKRLKQLS---------------LRRESPPTDQQII---------- 550
            :..|.|.::|:||::||..|:||.:|.               ||:...|.|.|..
Mouse   276 KEKEYEHEMERLAREKIATQQRLAELKHELSQWMDVLEIDRVLRQTGQPEDDQASTSTASEGEDN 340

  Fly   551 --------------------PQADKAVCLATTATTAP---PTAASGHNGTTILFDAGNAC----- 587
                                ||.:.......|.:|||   ||....|.....|..|....
Mouse   341 VDEEMEGDRAGLGPPKLNHRPQPELLKSALPTPSTAPAPLPTHPHPHPHPVALSPAHLPVQQQQP 405

  Fly   588 --------------ATGQLTTVINKTNGGATAAASSKHNGNHTGGATTTLTPAMGIMTIKNG-NG 637
                          ||...|.|....:..|||      .|..|..|.|..|.|..|.|:.:. .|
Mouse   406 PQQKTPLPAPPPPPATPTQTLVPAPAHLVATA------GGGSTVIAHTATTHASVIQTVNHVLQG 464

  Fly   638 SNGNMLA-ISPTG-GHNHQLHQHHNGSPAGSPSGIGATTGATITR----GSPTPSTPSPSPSSSS 696
            ..|..:| |:|:. ....||      :||..|.|......||:..    ||..|..|.|...|..
Mouse   465 PGGKHIAHIAPSAPSPAVQL------APATPPIGHITVHPATLNHVAHLGSQLPLYPQPVAVSQP 523

  Fly   697 SGVS 700
            ..||
Mouse   524 VAVS 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mnt	NP_001162651.1	HLH	457..512	CDD:238036	32/54 (59%)
Mnt	NP_034943.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	17..122		14/37 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	182..223		5/40 (13%)
		HLH	224..274	CDD:278439	7/50 (14%)
		Leucine-zipper	273..301		0/27 (0%)
		DUF2630	281..339	CDD:287859	4/57 (7%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	321..426		46/104 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	65	1.000	Domainoid score	I10037
eggNOG	1	0.900	-	-		E1_KOG2483
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006432
OrthoInspector	1	1.000	-	-		oto92759
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11969
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3297
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.900