DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mnt and Mxd3

DIOPT Version :9

Sequence 1:	NP_001162651.1	Gene:	Mnt / 31331	FlyBaseID:	FBgn0023215	Length:	790	Species:	Drosophila melanogaster
Sequence 2:	NP_057871.2	Gene:	Mxd3 / 17121	MGIID:	104987	Length:	206	Species:	Mus musculus

Alignment Length:	111	Identity:	42/111 - (37%)
Similarity:	64/111 - (57%)	Gaps:	7/111 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   430 SQLSAHHHTGHGGRRRTTSSNSNGA--GTREVHNKLEKERRAQLKECYDLLKKVLPMGDEDRKKT 492
            :.|..||..|...|||.....:.||  ..|.|||:|||.||||||.|.:.|::.:|:| .|..:.
Mouse    30 ASLCPHHSPGTVCRRRKPPLQAPGALNSGRSVHNELEKRRRAQLKRCLEQLRQQMPLG-VDCTRY 93

  Fly   493 SNLTILDTAHKYVNSLSHEVCEQEAK--IEKLAKQKIELQKRLKQL 536
            :.|::|..|..::..|..:  ||:|:  .|||..::..||::|:||
Mouse    94 TTLSLLRRARVHIQKLEEQ--EQQARRLKEKLRSKQQSLQQQLEQL 137

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mnt	NP_001162651.1	HLH	457..512	CDD:238036	22/54 (41%)
Mxd3	NP_057871.2	Interaction with SIN3A and SIN3B. /evidence=ECO:0000269\|PubMed:8521822	8..25
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	29..66		13/35 (37%)
		HLH	63..115	CDD:197674	20/54 (37%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	122..171		7/16 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2483
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3297
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.840