DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Parg and PARG2

DIOPT Version :9

Sequence 1:	NP_001245511.1	Gene:	Parg / 31329	FlyBaseID:	FBgn0023216	Length:	723	Species:	Drosophila melanogaster
Sequence 2:	NP_973578.1	Gene:	PARG2 / 817744	AraportID:	AT2G31865	Length:	532	Species:	Arabidopsis thaliana

Alignment Length:	452	Identity:	146/452 - (32%)
Similarity:	219/452 - (48%)	Gaps:	107/452 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   152 DEELDESETRVFFEDLLPRIIRLALRLPDLIQSPVPLLKHHKNAS-------------------- 196
            |:::...|:..||.:::|.:.||.|:||.:::      ||::.|.
plant    82 DKKISREESANFFGEVVPALCRLLLQLPSMLE------KHYQKADHVLDGVKSGLRLLGPQEAGI 140

  Fly   197 LSLSQQQISCLLANAFLCTFPR-RNTLKRKSEYSTFPDINFNRL----YQSTGPAVLEKLKCIMH 256
            :.|||:.|:.|||.:|.|.||. ..:||      ....|||:.|    |.........|:||::|
plant   141 VLLSQELIAALLACSFFCLFPEVDRSLK------NLQGINFSGLFSFPYMRHCTKQENKIKCLIH 199

  Fly   257 YFRRVCPTERDASNVPTGVVTFVRRSGLP----EHLI------DWSQSAAPLGDVPLHVDAEGTI 311
            ||.|:|..      :|||.|:|.|:. ||    .|.:      .|:.|..||..:.:|  ..|.|
plant   200 YFGRICRW------MPTGFVSFERKI-LPLEYHPHFVSYPKADSWANSVTPLCSIEIH--TSGAI 255

  Fly   312 EDEGIGLLQVDFANKYLGGGVLGHGCVQEEIRFVICPELLVGKLFTECLRPFEALVMLGAERYSN 376
            ||:....|:||||::|.||..|.:..:||||||||.|||:.|.:|...:...||:.::|.||:|.
plant   256 EDQPCEALEVDFADEYFGGLTLSYDTLQEEIRFVINPELIAGMIFLPRMDANEAIEIVGVERFSG 320

  Fly   377 YTGYAGSFEWSGNFEDSTPRDSSGRRQTAIVAIDALHFAQSHHQYREDLMERELNKAYIGFVH-- 439
            ||||..||:::|::.|:...|...||:|.::||||:. .....||:.|.:.||:|||:.|::|
plant   321 YTGYGPSFQYAGDYTDNKDLDIFRRRKTRVIAIDAMP-DPGMGQYKLDALIREVNKAFSGYMHQC 384

  Fly   440 -------------------------------------------WMVTPPP---GVATGNWGCGAF 458
                                                       |.:....   ||||||||||.|
plant   385 KYNIDVKHDPEASSSTKIKFVFAKQHVPLTSDSASQVIESSHRWCIDHEEKKIGVATGNWGCGVF 449

  Fly   459 GGDSYLKALLQLMVCAQLGRP-LAYYTFGNVEFRDDFHEMWLLFRNDGTTVQQLWSILRSYS 519
            |||..||.:||.:..:|.||| ::||||| ::...:.:::..:......||..||..|..||
plant   450 GGDPELKIMLQWLAISQSGRPFMSYYTFG-LQALQNLNQVIEMVALQEMTVGDLWKKLVEYS 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Parg	NP_001245511.1	PARG_cat	155..492	CDD:282834	138/420 (33%)
PARG2	NP_973578.1	PARG_cat	85..484	CDD:282834	138/421 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	247	1.000	Domainoid score	I540
eggNOG	1	0.900	-	-		E1_KOG2064
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	263	1.000	Inparanoid score	I960
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D730627at2759
OrthoFinder	1	1.000	-	-		FOG0004062
OrthoInspector	1	1.000	-	-		otm2449
orthoMCL	1	0.900	-	-		OOG6_102366
Panther	1	1.100	-	-	O	PTHR12837
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2814
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.830