DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2875 and noc4l

DIOPT Version :9

Sequence 1:	NP_570069.1	Gene:	CG2875 / 31326	FlyBaseID:	FBgn0029672	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	XP_012815758.2	Gene:	noc4l / 493276	XenbaseID:	XB-GENE-6458094	Length:	525	Species:	Xenopus tropicalis

Alignment Length:	514	Identity:	156/514 - (30%)
Similarity:	259/514 - (50%)	Gaps:	56/514 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 KLQSKANSLLNAEQV-DIKTLKGFVQLLKNTPDNMPAGEVMNTLEVIFKNLLKRKAIDG------ 77
            ||.:...|..||..| ||      ::.|::..:.:....:..|.::....|.||:...|
Frog    27 KLAAVLGSRTNANAVFDI------LEHLESKKEEVVQAAIRTTSKLFEVFLEKRELYIGDLPAED 85

  Fly    78 ---------TEKQGLKIKKLYEETWLLLIENLLVDSQCSV---AVKVCMQLIKVEAKHPIAPNKG 130
                     .:|..:.::..|......|: |||..|..||   |:...|:.|::|.|.|: .|..
Frog    86 DSLPDTCSAEDKYKMWMRHRYNSCVTCLL-NLLQHSSFSVQELALCTLMKFIQLEGKFPL-ENSE 148

  Fly   131 W------PTYWIRGMLETLINSDTTPTTALANYGKYCKNLDVLEITLTQLKSLVPDEDFKDSPIK 189
            |      |...::.:::.|:..:|..|..:..:.:|.:..||...|:|.....:.....|...:.
Frog   149 WKESYRFPIELLKFVIDNLLQEETDSTLLITRFQEYLEYDDVRYYTMTATNDCIARVQQKTKQVL 213

  Fly   190 AMNFLSIVNLLDMGKSVLSTADYHVESAKKQTF------NYE-------LNRKRL-NNLWATIMA 240
            ...|.:.|..|      ||:.:..||.:..:.|      |:|       ...||: ..:|.:.:.
Frog   214 PPVFQTNVFCL------LSSINMPVEQSSLENFLVTKNANHEDWKPTKLKEHKRVFERVWMSFLK 272

  Fly   241 KGNEVDEKLHRQILVVLLERVINHLNDPIQLTDFLMDSLHQFDGPIALLALQGIFTLMQKQNITY 305
              :::...|::::|::|.|.::.|::.|..:.||| .:.:...|.|:||||.|:|.|:.:.|:.|
Frog   273 --HQLSVSLYKKVLLILHESILPHMSKPTLMIDFL-TAAYDVGGAISLLALNGLFILIHQHNLEY 334

  Fly   306 PDVYEKLYNMFYPRMFHNKYKARLFYLADIFLTSTHLPENLVAAFVKRLARLALQSPTEDAVIMI 370
            ||.|:|||::..|.:||.||:||.|:||::||:|||||..|||||.||||||.|.:|.:..:::|
Frog   335 PDFYKKLYSLLEPSIFHVKYRARFFHLANLFLSSTHLPIYLVAAFAKRLARLTLTAPPQVLLMII 399

  Fly   371 RFVCNLLLRHTGLQKLIRASHAVDEVSDPYNQTETDPVKSEAINSSLWEITLLQKHVVPEVANAA 435
            .|:|||:.||...:.||...:..|..:|||...|.||.||:|:.|||||:.:||:|...:|..||
Frog   400 PFICNLIRRHPACRALIHRPNTGDLATDPYIMEEQDPAKSQALESSLWELEVLQQHYHGDVVRAA 464

  Fly   436 RFINSSLPVMEFDLAPLLDRKECNIFDDELQSKAKQFALNYERPTNLALPKNQFVTKYW 494
            ..|:.:|...|.|::.||:.....:||.|::.|.|...|.||....|...|:....:::
Frog   465 NVISRALSAQESDISGLLEISSSELFDKEMKKKFKSVPLEYEPVRGLLGLKSDITAEHF 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2875	NP_570069.1	CBF	287..435	CDD:281851	73/147 (50%)
noc4l	XP_012815758.2	CBF	316..464	CDD:397822	73/147 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	157	1.000	Domainoid score	I4111
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	223	1.000	Inparanoid score	I3436
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D251577at33208
OrthoFinder	1	1.000	-	-		FOG0004812
OrthoInspector	1	1.000	-	-		oto103862
Panther	1	1.100	-	-	LDO	PTHR12455
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1838
SonicParanoid	1	1.000	-	-		X3394
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.100