DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2875 and Noc4l

DIOPT Version :9

Sequence 1:	NP_570069.1	Gene:	CG2875 / 31326	FlyBaseID:	FBgn0029672	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_001014151.1	Gene:	Noc4l / 360828	RGDID:	1310661	Length:	516	Species:	Rattus norvegicus

Alignment Length:	502	Identity:	145/502 - (28%)
Similarity:	249/502 - (49%)	Gaps:	58/502 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 KPLTVKVNDDTGKSL-AKKKLQSKANSLLNAEQVDIKTLKGFVQLLKNTPDNMPAGEVMNTLEVI 65
            :|.:.....:.|:.| |....:.:||::.:...|          |....|:.:..|  :.|...:
  Rat     4 QPASTGSRQELGRLLEAVLSNRGRANAVFDILAV----------LQSEDPEEIKEG--VRTCSRL 56

  Fly    66 FKNLLKRK------------AIDGTEKQGLKIKKLYEETWLL--------LIENLLVDSQCSV-- 108
            |..||:|:            |:.|::....|.|     .|:.        .:|.||......|
  Rat    57 FGTLLEREELFVGSLPCEDMALAGSQGATYKYK-----VWMRHRYHSCCNRLEELLTHPSFQVKE 116

  Fly   109 -AVKVCMQLIKVEAKHPIAPNKGWPTYWI--RGMLETLINSDTTP----TTALANYGKYCKNLDV 166
             |::..|:.:::|...|:...: |.::::  |.:...::....||    :..::.:.:|.:..|:
  Rat   117 LALETLMKFVQLEGAKPLEKPQ-WESHYLFPRTLFRAVVGGLLTPEDDHSLLISQFCEYLEYDDI 180

  Fly   167 LEITLTQLKSLVPDEDFKDSPI------KAMNFLSIVNLLDMGKSVLSTADYHVE-SAKKQTFNY 224
            ....:....|::.....:...:      .|...||.|||......:.:....|.: |:|.:..:.
  Rat   181 RYHAMQVATSILARATSRQPEVSLTFWNNAFTLLSAVNLPLQEHELTNFYVKHAQTSSKWKVVHL 245

  Fly   225 ELNRKRLNNLWATIMAKGNEVDEKLHRQILVVLLERVINHLNDPIQLTDFLMDSLHQFDGPIALL 289
            :..||....:|...:.  :::...|::::||.:.:.::.||..|..:.||| .|.....|.|:||
  Rat   246 KEQRKAFQEMWLGFLK--HKLPLSLYKKVLVAMHDSILPHLAQPTLMIDFL-TSACDVGGAISLL 307

  Fly   290 ALQGIFTLMQKQNITYPDVYEKLYNMFYPRMFHNKYKARLFYLADIFLTSTHLPENLVAAFVKRL 354
            ||.|:|.|:.|.|:.|||.|::||.:..|.:||.||:||.|:|||:||:|:|||..|||||.|||
  Rat   308 ALNGLFILIHKHNLEYPDFYQRLYGLLDPSIFHVKYRARFFHLADLFLSSSHLPAYLVAAFAKRL 372

  Fly   355 ARLALQSPTEDAVIMIRFVCNLLLRHTGLQKLIRASHAVDEVSDPYNQTETDPVKSEAINSSLWE 419
            |||||.:|.|..::::..:||||.||...:.::......:..:|||:.||.||.:|.|:.|.|||
  Rat   373 ARLALTAPPEALLMVLPLICNLLRRHPACRVMVHRPQGPELDADPYDPTEKDPARSRALESCLWE 437

  Fly   420 ITLLQKHVVPEVANAARFINSSLPVMEFDLAPLLDRKECNIFDDELQ 466
            :..||:|..|||:.||..||.:|.|.|..:||||:.....||:.:|:
  Rat   438 LQTLQQHYHPEVSRAASVINQALSVPEVSIAPLLELTAYEIFEQDLK 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2875	NP_570069.1	CBF	287..435	CDD:281851	72/147 (49%)
Noc4l	NP_001014151.1	NOC3	<96..453	CDD:227447	111/360 (31%)
Noc4l	NP_001014151.1	CBF	305..453	CDD:281851	72/147 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340810
Domainoid	1	1.000	158	1.000	Domainoid score	I4050
eggNOG	1	0.900	-	-		E1_KOG2154
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H40545
Inparanoid	1	1.050	208	1.000	Inparanoid score	I3619
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D251577at33208
OrthoFinder	1	1.000	-	-		FOG0004812
OrthoInspector	1	1.000	-	-		oto97170
orthoMCL	1	0.900	-	-		OOG6_102386
Panther	1	1.100	-	-	LDO	PTHR12455
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3394
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.760