DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-alpha and opcml

DIOPT Version :9

Sequence 1:	NP_001259218.1	Gene:	DIP-alpha / 31322	FlyBaseID:	FBgn0052791	Length:	554	Species:	Drosophila melanogaster
Sequence 2:	NP_001072487.1	Gene:	opcml / 779942	XenbaseID:	XB-GENE-5831850	Length:	346	Species:	Xenopus tropicalis

Alignment Length:	339	Identity:	99/339 - (29%)
Similarity:	158/339 - (46%)	Gaps:	37/339 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 CDRNGKMLIHLLLIVSLLEAIGAFQPEFVESISNVSVAVGRDATFTCHVRHLGGYRVGWLKADTK 81
            |...|..|..||.|..:  .:.:....|.:::.||:|..|..|...|.|.: ...||.||...|
Frog    15 CWMFGAALTVLLSITGV--PVRSGDAGFPKAMDNVTVRQGDSAILRCTVDN-RVTRVAWLNRST- 75

  Fly    82 AIQAIHENVITHNPRVTVSHLDQNTWNLHIKAVSEEDRGGYMCQLNTD--PMKSQIGFLDVVIPP 144
             |.....:..:.:|||.:....::.:::.|:.|...|.|.|.|.:.||  |..|:: .|.|.:.|
Frog    76 -ILYTGNDKWSIDPRVVLLANTKSQYSIEIQNVDIYDEGPYTCSVQTDNHPKTSRV-HLIVQVAP 138

  Fly   145 DFISEDTSSDVIVPEGSSVRLTCRARGYPEPIVTWRREDG--NEIVLKDNVGTKTLAPSFRGEVL 207
            ..:  :.|||:.|.|||:|.|.|.|.|.|||.||||...|  :..|..|             |.|
Frog   139 QIL--NISSDITVNEGSTVALRCLATGRPEPAVTWRHFTGKSHRFVSDD-------------EYL 188

  Fly   208 KLSKISRNEMGSYLCIASNGVPPSVSKRISLSIHFHPVIQVPNQLVGAPLGTDVQIECHVEASPK 272
            :::.|:|::.|.|.|.|:|.|.....:::.:::::.|.|. ..:..||.||....:.|...|.|.
Frog   189 EITGITRDQSGQYECSAANDVSAPDIRKVRVTVNYPPYIS-DTRNTGASLGQKGILRCSASAVPL 252

  Fly   273 SINYWIKDTGEMIVTSGKYHVQESSQSMYETKMSMIVRKF---QKDDVGSYRCIAKNSLGEVDSS 334
            :...|.::  |..:.:|...|:      .|.|..|.:..|   .:.|.|:|.|:|.|.||..::|
Frog   253 AEFQWYRE--ETRLANGLDGVR------IENKDHMSILTFFNVSEKDYGNYTCVASNKLGNSNAS 309

  Fly   335 IRLYEIPGPNRNKN 348
            :.||..||...|::
Frog   310 VILYAGPGAIHNRS 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-alpha	NP_001259218.1	IG_like	49..129	CDD:214653	22/79 (28%)
		Ig	51..131	CDD:299845	23/81 (28%)
		I-set	144..240	CDD:254352	33/97 (34%)
		IGc2	159..228	CDD:197706	27/70 (39%)
		Ig	244..337	CDD:299845	26/95 (27%)
		I-set	244..337	CDD:254352	26/95 (27%)
opcml	NP_001072487.1	Ig	46..134	CDD:325142	27/91 (30%)
		Ig_3	138..207	CDD:316449	31/83 (37%)
		ig	228..312	CDD:278476	24/92 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	58	1.000	Domainoid score	I10578
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	138	1.000	Inparanoid score	I4412
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.060