DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-alpha and zgc:152904

DIOPT Version :9

Sequence 1:	NP_001259218.1	Gene:	DIP-alpha / 31322	FlyBaseID:	FBgn0052791	Length:	554	Species:	Drosophila melanogaster
Sequence 2:	NP_001070212.1	Gene:	zgc:152904 / 767777	ZFINID:	ZDB-GENE-060929-856	Length:	809	Species:	Danio rerio

Alignment Length:	290	Identity:	70/290 - (24%)
Similarity:	122/290 - (42%)	Gaps:	33/290 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 NVSVAVGRDATFTCHVRHLGGYRVGWLKADTKAIQAIHENVITHNPRVTVSHLDQNTWNLHIKAV 114
            |.:.......||||........:|.|....         :.|.|:.:..::.::.....|.:|.:
Zfish   188 NATADYQESVTFTCVTSGSPDPQVTWYWKG---------HAIEHSEQYVLNTMNGGKSTLTVKNI 243

  Fly   115 SEEDRGGYMCQLN--TDPMKSQIGFLDVVIPPDFISEDTSSDVIVPEGSSVRLTCRARGYPEPIV 177
            .:.|.|.|||:.:  ....:||: ||.|.:.|....   ..:|...|||:..::|.|.|.|.|.:
Zfish   244 KQTDGGPYMCRASNKAGSSESQL-FLKVFVQPHITQ---LRNVTAVEGSAAMISCTAEGEPLPEI 304

  Fly   178 TWRR-EDGNEIVLKDNVGTKTLAPSFRG----EVLKLSKISRNEMGSYLCIASNGVPPSVSKRIS 237
            :||| .||:...  |...:|......||    .:|.:|.:..::.|.:.|.|.:.: ....|.:.
Zfish   305 SWRRASDGHSFT--DGEKSKDGRVEVRGRHGKSMLTISGVQLSDWGRFDCEALSRI-GGHQKSMF 366

  Fly   238 LSIHFHPVIQVPNQLVGAPLGTDVQIECHVEASPKSINYWIKDTGEMIVTSGKYHVQESS---QS 299
            |.|.:.|..|....:..:..|..|.|.|.|:::|.:...|.::. ..|.:.|..:::..|   :|
Zfish   367 LDIEYAPKFQTNQSIFYSWEGNPVNISCEVKSNPAATMLWRRER-FTISSQGTSNIRIHSTDGRS 430

  Fly   300 MYETKMSMIVRKFQKDDVGSYRCIAKNSLG 329
            :.|      |......|.|.|.|.|:|::|
Zfish   431 LLE------VTPVSDRDFGRYNCTARNNIG 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-alpha	NP_001259218.1	IG_like	49..129	CDD:214653	16/80 (20%)
		Ig	51..131	CDD:299845	15/81 (19%)
		I-set	144..240	CDD:254352	26/100 (26%)
		IGc2	159..228	CDD:197706	22/73 (30%)
		Ig	244..337	CDD:299845	22/89 (25%)
		I-set	244..337	CDD:254352	22/89 (25%)
zgc:152904	NP_001070212.1	Ig	1..81	CDD:299845
		IG_like	2..80	CDD:214653
		IGc2	97..158	CDD:197706
		Ig	177..273	CDD:299845	21/94 (22%)
		I-set	184..270	CDD:254352	20/91 (22%)
		Ig	272..369	CDD:299845	26/102 (25%)
		I-set	274..367	CDD:254352	25/98 (26%)
		IG_like	385..462	CDD:214653	20/77 (26%)
		IGc2	386..454	CDD:197706	19/74 (26%)
		FN3	468..561	CDD:238020
		fn3	<591..650	CDD:278470
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12231
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010