DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-alpha and Kirrel3

DIOPT Version :9

Sequence 1:NP_001259218.1 Gene:DIP-alpha / 31322 FlyBaseID:FBgn0052791 Length:554 Species:Drosophila melanogaster
Sequence 2:XP_006510620.1 Gene:Kirrel3 / 67703 MGIID:1914953 Length:803 Species:Mus musculus


Alignment Length:403 Identity:92/403 - (22%)
Similarity:155/403 - (38%) Gaps:107/403 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 AKRLLRNFQFTSCDRNGKMLIHLLLIVSLLEAIGAFQPEFVES-------ISNVSVAVGRDATFT 62
            :|.|||       |...:.::..|.|          .|..||:       .:|.::..|::.:.|
Mouse   196 SKTLLR-------DGKRESIVSTLFI----------SPGDVENGQSIVCRATNKAIPGGKETSVT 243

  Fly    63 CHVRHLGGYRVGWLKADTKAIQAIHENVITH------NPRVTVSHLDQNTWNLHIKAVSEEDRGG 121
            ..::|     ...:....:....:.:|::|.      ||.||     |..|......:.|.....
Mouse   244 IDIQH-----PPLVNLSVEPQPVLEDNIVTFHCSAKANPAVT-----QYRWAKRGHIIKEASGEL 298

  Fly   122 YMCQLN----TDPMKSQI----------GFLDVVIPPDFISEDTSSDVIVPEGSSVRLTCRARGY 172
            |...::    ::|:..::          ..:||...|...||..|  ::|..||....:|...|.
Mouse   299 YRTTVDYTYFSEPVSCEVTNALGSTNLSRTVDVYFGPRMTSEPQS--LLVDLGSDAVFSCAWIGN 361

  Fly   173 PEPIVTWRREDGNEIVLKDNVGTKTLAPSFRGEVLKLSKISRNEMGSYLCIASNGVPPSV---SK 234
            |...:.|.:. |:.:||.:.   |||.         |..:.:.:.|.|:|.|   |.|.|   .:
Mouse   362 PSLTIVWMKR-GSGVVLSNE---KTLT---------LKSVRQEDAGKYVCRA---VVPRVGAGER 410

  Fly   235 RISLSIHFHPVIQVPNQLVGAPLGTDVQIECHVEASPKSINY---W---IKDTGEMIVTSGKYHV 293
            .::|:::..|:|. ..|...|..|...||:|.:.::|.....   |   :.::|    |||:|.|
Mouse   411 EVTLTVNGPPIIS-STQTQHALHGEKGQIKCFIRSTPPPDRIAWSWKENVLESG----TSGRYTV 470

  Fly   294 Q--ESSQSMYET-KMSMIVR-KFQKDDVGSYRCIAKNSLGEVDSSIRLYEIPGPNRNKNPLNGGG 354
            :  .:.:.:..| .:|.||| .||.    .|.|.|.||.|.....|||.|           .|..
Mouse   471 ETVNTEEGVISTLTISNIVRADFQT----IYNCTAWNSFGSDTEIIRLKE-----------QGSE 520

  Fly   355 KGGGAGGSLDADA 367
            ...|||  |:|::
Mouse   521 MKSGAG--LEAES 531

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-alphaNP_001259218.1 IG_like 49..129 CDD:214653 14/89 (16%)
Ig 51..131 CDD:299845 13/89 (15%)
I-set 144..240 CDD:254352 26/98 (27%)
IGc2 159..228 CDD:197706 17/68 (25%)
Ig 244..337 CDD:299845 30/102 (29%)
I-set 244..337 CDD:254352 30/102 (29%)
Kirrel3XP_006510620.1 IG_like 54..143 CDD:214653
Ig strand A' 56..60 CDD:409353
Ig strand B 64..71 CDD:409353
Ig strand C 78..82 CDD:409353
Ig strand C' 84..87 CDD:409353
Ig strand D 97..101 CDD:409353
Ig strand E 104..116 CDD:409353
Ig strand G 132..143 CDD:409353
IgI_2_KIRREL3-like 149..246 CDD:409416 13/66 (20%)
Ig strand B 166..170 CDD:409416
Ig strand C 180..184 CDD:409416
Ig strand E 210..214 CDD:409416 1/3 (33%)
Ig strand F 224..229 CDD:409416 0/4 (0%)
Ig strand G 239..242 CDD:409416 0/2 (0%)
Ig <267..334 CDD:416386 12/71 (17%)
Ig strand B 267..274 CDD:409353 1/6 (17%)
Ig strand C 279..286 CDD:409353 4/11 (36%)
Ig strand C' 288..291 CDD:409353 0/2 (0%)
Ig strand D 298..302 CDD:409353 1/3 (33%)
Ig strand E 304..310 CDD:409353 0/5 (0%)
Ig strand G 321..334 CDD:409353 2/12 (17%)
Ig 335..416 CDD:416386 26/98 (27%)
Ig strand A' 343..347 CDD:409353 1/5 (20%)
Ig strand B 350..360 CDD:409353 2/9 (22%)
Ig strand C 365..371 CDD:409353 1/5 (20%)
Ig strand E 381..387 CDD:409353 4/14 (29%)
IgI_5_KIRREL3 418..515 CDD:409479 31/105 (30%)
Ig strand B 436..440 CDD:409479 2/3 (67%)
Ig strand C 450..454 CDD:409479 0/3 (0%)
Ig strand E 481..485 CDD:409479 1/3 (33%)
Ig strand F 496..501 CDD:409479 2/4 (50%)
Ig strand G 509..512 CDD:409479 0/2 (0%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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