DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-alpha and lsamp

DIOPT Version :9

Sequence 1:	NP_001259218.1	Gene:	DIP-alpha / 31322	FlyBaseID:	FBgn0052791	Length:	554	Species:	Drosophila melanogaster
Sequence 2:	NP_001034921.1	Gene:	lsamp / 664692	ZFINID:	ZDB-GENE-090108-1	Length:	333	Species:	Danio rerio

Alignment Length:	355	Identity:	97/355 - (27%)
Similarity:	150/355 - (42%)	Gaps:	68/355 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 SCDRNGKMLIHLLLIVSL-----LEAIGAFQPEFVESISNVSVAVGRDATFTCHVRHLGGYRVGW 75
            ||     :.||.:.|...     .|.......|...|..|:::..|......|:|..... :|.|
Zfish     2 SC-----LWIHSVFIPGFFLLFGFEGFPVISVESQRSTDNITIRQGDTTVIRCYVDDKVS-KVAW 60

  Fly    76 LKADTKAIQAIHENVI-------THNPRVTVSHLDQNTWNLHIKAVSEEDRGGYMCQLNTDPMK- 132
            |.         ..|:|       :.:|||.:....|..::|.|:.|...|.|.|.|.:.|....
Zfish    61 LN---------RSNIIFAGEDKWSLDPRVELVTQGQLEYSLRIQKVDVFDEGPYTCSIQTKQQSK 116

  Fly   133 -SQIGFLDVVIPPDFISEDTSSDVIVPEGSSVRLTCRARGYPEPIVTWRREDGNEIVLKDNVGTK 196
             ||: :|.|.:|.  |....|.|:.|.|||:|.|||.|.|.|:|.:|||
Zfish   117 TSQV-YLIVQVPA--IIYKVSEDITVNEGSNVALTCLANGRPDPAITWR---------------- 162

  Fly   197 TLAPSFR----GEVLKLSKISRNEMGSYLCIASNGVPPSVSKRISLSIHFHPVIQVPNQLVGAPL 257
            .|.||..    ||.|::|.:.|::.|.|.|.|||.|.....|.:::.:::.|.|:.......| :
Zfish   163 LLNPSAEALDVGEYLEISGVVRSQAGRYECKASNDVSTPDVKYVNVVVNYPPYIKDVRSSETA-V 226

  Fly   258 GTDVQIECHVEASPKSINYWIKDTGEMIVTSGKYHVQESSQSM----YETKMSMIVRKFQKDDVG 318
            |....:.|...|.|:....|.:|...:          .||||:    ..::..::|....::|.|
Zfish   227 GQAGVLHCEASAVPQPEFEWYRDERRL----------SSSQSLTIQVSGSRTVLVVANVTEEDYG 281

  Fly   319 SYRCIAKNSLGEVDSSIRLYEIPGPNRNKN 348
            :|.|:|.|.||..::|:.||: ||..|:.|
Zfish   282 NYTCVATNRLGVHNASVFLYK-PGMGRDIN 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-alpha	NP_001259218.1	IG_like	49..129	CDD:214653	20/86 (23%)
		Ig	51..131	CDD:299845	20/86 (23%)
		I-set	144..240	CDD:254352	34/99 (34%)
		IGc2	159..228	CDD:197706	28/72 (39%)
		Ig	244..337	CDD:299845	23/96 (24%)
		I-set	244..337	CDD:254352	23/96 (24%)
lsamp	NP_001034921.1	Ig	34..124	CDD:299845	24/100 (24%)
		IG_like	36..124	CDD:214653	24/98 (24%)
		IG_like	134..197	CDD:214653	30/78 (38%)
		IGc2	141..199	CDD:197706	28/73 (38%)
		I-set	213..300	CDD:254352	23/97 (24%)
		Ig	231..298	CDD:143165	18/76 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010