DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-alpha and igsf9a

DIOPT Version :9

Sequence 1:	NP_001259218.1	Gene:	DIP-alpha / 31322	FlyBaseID:	FBgn0052791	Length:	554	Species:	Drosophila melanogaster
Sequence 2:	XP_005155702.1	Gene:	igsf9a / 557459	ZFINID:	ZDB-GENE-060503-288	Length:	1619	Species:	Danio rerio

Alignment Length:	296	Identity:	76/296 - (25%)
Similarity:	125/296 - (42%)	Gaps:	52/296 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 YRVGWLKA--DTKAIQ--AIHENVITHNPRVTVSHLDQN-------TWNLHIKAVSEEDRGGYMC 124
            |.:.|::.  ||....  .:|       |||   |.|.:       ..:|.:..:..||.|.|.|
Zfish    55 YVIEWVRQGFDTPIFMQLGVH-------PRV---HPDYDGRVSLFGGTSLQMSGLQLEDEGWYEC 109

  Fly   125 Q-LNTDPMKSQIGF------LDVVIPPDFISEDTSSDVIVPEGSSVRLTCRARGYPEPIVTWRRE 182
            : |..|....:.|.      |.|..|| .::|.:..:|.|..|.|:.|.|.|:|.|.|.:||.:
Zfish   110 RILPLDQTTEEAGSSGSWTRLSVTAPP-VLTETSPPEVEVFVGRSLTLKCAAQGNPRPTITWSK- 172

  Fly   183 DGNEIVLKDNVGTKTLAPSFRGEVLKLSKISRNEMGSYLCIASN--GVPPSVSKRISLSIHFHPV 245
            ||..|..:..|.....:.||..       :||...|.|.|..||  |....|::   |.|...||
Zfish   173 DGAPIKPQHKVKMVNGSVSFHA-------VSREAAGQYQCYTSNSEGNATHVTR---LKIIGPPV 227

  Fly   246 IQVPNQLVGAPLGTDVQIECHVEASPKSINY-WIKDTGEMIVTSGKYHVQESSQSMYETKM--SM 307
            |.:|.......:..|.:::|..||.|.::.| |.:...::      ||: :|.:|..:..:  ::
Zfish   228 IIIPPSDTVLNMSQDAKLKCQAEADPPNMTYVWQRQGVDI------YHI-DSLKSRIKVIVDGTL 285

  Fly   308 IVRKFQKDDVGSYRCIAKNSLGEVDSSIRLYEIPGP 343
            ::.:...:|.|:|.|:..|.|....|:..:..:..|
Zfish   286 LISRLAPEDSGNYTCMPTNGLPVSPSASAVLTVQHP 321

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-alpha	NP_001259218.1	IG_like	49..129	CDD:214653	17/69 (25%)
		Ig	51..131	CDD:299845	18/71 (25%)
		I-set	144..240	CDD:254352	30/97 (31%)
		IGc2	159..228	CDD:197706	23/70 (33%)
		Ig	244..337	CDD:299845	22/95 (23%)
		I-set	244..337	CDD:254352	22/95 (23%)
igsf9a	XP_005155702.1	IG_like	27..110	CDD:214653	15/64 (23%)
		Ig	35..111	CDD:299845	16/65 (25%)
		I-set	140..221	CDD:254352	28/91 (31%)
		IGc2	151..212	CDD:197706	23/68 (34%)
		Ig	233..318	CDD:299845	18/91 (20%)
		I-set	233..318	CDD:254352	18/91 (20%)
		Ig	<349..402	CDD:299845
		IG_like	423..502	CDD:214653
		Ig	435..498	CDD:143165
		FN3	507..602	CDD:238020
		fn3	614..696	CDD:278470
		PHA02666	1105..>1312	CDD:222914
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900