DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-alpha and KIRREL1

DIOPT Version :9

Sequence 1:NP_001259218.1 Gene:DIP-alpha / 31322 FlyBaseID:FBgn0052791 Length:554 Species:Drosophila melanogaster
Sequence 2:XP_005245362.1 Gene:KIRREL1 / 55243 HGNCID:15734 Length:773 Species:Homo sapiens


Alignment Length:336 Identity:82/336 - (24%)
Similarity:133/336 - (39%) Gaps:61/336 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    23 MLIHLLLIVSLLEAIG-AFQPEFVESISNVSVAVGRDATFTCHVRHLGGYRVGWLKADTKAI--- 83
            ||..|:.|::|.:... ..|..|.:..::.:|..|:.|...|.:.:..|. |.|.| |..|:   
Human     1 MLSLLVWILTLSDTFSQGTQTRFSQEPADQTVVAGQRAVLPCVLLNYSGI-VQWTK-DGLALGMG 63

  Fly    84 QAIHENVITHNPRV-TVSHLDQNTWNLHIKAVSEEDRGGYMCQLNTDPMKSQIGFLDVVIPPDFI 147
            |.:..     .||. .|...|...:||.|......|...|.||.....::|:...|.|:|||   
Human    64 QGLKA-----WPRYRVVGSADAGQYNLEITDAELSDDASYECQATEAALRSRRAKLTVLIPP--- 120

  Fly   148 SEDTSSD----VIVPEGSSVRLTCRA-RGYPEPIVTWRREDGNEIVLKDNVGTKTLAPSFRGEVL 207
             |||..|    :::..|:...||||| ...|...:.|.|:           ||:........|:|
Human   121 -EDTRIDGGPVILLQAGTPHNLTCRAFNAKPAATIIWFRD-----------GTQQEGAVASTELL 173

  Fly   208 K-------LSKISRN----EMGS-YLCIASN-GVPPSVSKRISLSIHFHPVIQVPNQLVGAPLGT 259
            |       :|::..|    ::|. :.|.:.| .:|......|.|.:|..|.:.:..:......|.
Human   174 KDGKRETTVSQLLINPTDLDIGRVFTCRSMNEAIPSGKETSIELDVHHPPTVTLSIEPQTVQEGE 238

  Fly   260 DVQIECHVEASPKSINY-WIKDTGEMIVTSGKYHVQESSQSMYETKMSMIVRKFQKDDVGSYRCI 323
            .|...|...|:|:.:.| |.|         |.:.::::.:|.|||.:..   .|..:.|.   |.
Human   239 RVVFTCQATANPEILGYRWAK---------GGFLIEDAHESRYETNVDY---SFFTEPVS---CE 288

  Fly   324 AKNSLGEVDSS 334
            ..|.:|..:.|
Human   289 VHNKVGSTNVS 299

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-alphaNP_001259218.1 IG_like 49..129 CDD:214653 22/83 (27%)
Ig 51..131 CDD:299845 22/83 (27%)
I-set 144..240 CDD:254352 27/113 (24%)
IGc2 159..228 CDD:197706 19/82 (23%)
Ig 244..337 CDD:299845 20/92 (22%)
I-set 244..337 CDD:254352 20/92 (22%)
KIRREL1XP_005245362.1 I-set 22..116 CDD:254352 25/100 (25%)
Ig 25..116 CDD:299845 24/97 (25%)
Ig2_KIRREL3-like 138..219 CDD:143236 21/91 (23%)
I-set 223..304 CDD:254352 20/92 (22%)
Ig_2 227..305 CDD:290606 19/88 (22%)
Ig_2 311..405 CDD:290606
IG_like 314..405 CDD:214653
Ig5_KIRREL3 407..504 CDD:143306
IG_like 416..504 CDD:214653
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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