DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-alpha and dpr12

DIOPT Version :9

Sequence 1:	NP_001259218.1	Gene:	DIP-alpha / 31322	FlyBaseID:	FBgn0052791	Length:	554	Species:	Drosophila melanogaster
Sequence 2:	NP_652462.3	Gene:	dpr12 / 50320	FlyBaseID:	FBgn0085414	Length:	326	Species:	Drosophila melanogaster

Alignment Length:	213	Identity:	60/213 - (28%)
Similarity:	90/213 - (42%)	Gaps:	32/213 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 PEFVES---ISNVSVAVGRDATFTCHVRHLGGYRVG-------WLKADTKAIQAIHENVITHNPR 96
            |.|.:|   ..|.:|.:|..|...|.|.  |..|||       |::.....|.:....:.|::.|
  Fly    75 PMFEDSELMAHNTTVQLGGTAFLVCKVS--GVDRVGVNWNQISWIRRRDWHILSSGAQLYTNDER 137

  Fly    97 VTVSHL-DQNTWNLHIKAVSEEDRGGYMCQLNTDP-MKSQIGFLDVVIPPDFISEDTSSDVIVPE 159
            ..:.|. ..|.|.|.||.|...|.|.|.||::|.. :.|....|.||:|..||.  .|.::.|..
  Fly   138 FAILHTPGSNMWTLQIKFVQRRDHGMYECQVSTPTGIISHFVNLQVVVPEAFIL--GSGELHVDM 200

  Fly   160 GSSVRLTCRARGYPEP--IVTWRRED--------GNEIVLKDNVGTKTLAPSFRGEVLKLSKISR 214
            ||::.|.|.....|.|  .|.|::.|        ..:|.::...|.:|.:.      |.:.:...
  Fly   201 GSTINLVCIIEKSPTPPQYVYWQKNDRLINYVDSRRDITIETTPGPRTQSR------LIIREPQV 259

  Fly   215 NEMGSYLCIASNGVPPSV 232
            .:.|:|.|.|||..|.|:
  Fly   260 TDSGNYTCSASNTEPASI 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-alpha	NP_001259218.1	IG_like	49..129	CDD:214653	26/87 (30%)
		Ig	51..131	CDD:299845	26/88 (30%)
		I-set	144..240	CDD:254352	25/99 (25%)
		IGc2	159..228	CDD:197706	19/78 (24%)
		Ig	244..337	CDD:299845
		I-set	244..337	CDD:254352
dpr12	NP_652462.3	IG	86..183	CDD:214652	29/98 (30%)
		Ig_3	193..271	CDD:404760	19/83 (23%)
		Ig strand B	204..208	CDD:409353	1/3 (33%)
		Ig strand C	219..223	CDD:409353	1/3 (33%)
		Ig strand E	250..254	CDD:409353	1/9 (11%)
		Ig strand F	264..269	CDD:409353	2/4 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I11916
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810