DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DIP-alpha and dpr6

DIOPT Version :9

Sequence 1:	NP_001259218.1	Gene:	DIP-alpha / 31322	FlyBaseID:	FBgn0052791	Length:	554	Species:	Drosophila melanogaster
Sequence 2:	NP_001287018.1	Gene:	dpr6 / 50296	FlyBaseID:	FBgn0040823	Length:	396	Species:	Drosophila melanogaster

Alignment Length:	200	Identity:	58/200 - (28%)
Similarity:	91/200 - (45%)	Gaps:	12/200 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 QPEFVESI-SNVSVAVGRDATFTCHVRHLGGYRVGWLKADTKAIQAIHENVITHNPRVTVS-HLD 103
            :|.|..|. .||:..:|:.|..:|.||:|....|.|::.....|..:.....|.:.|...: |.|
  Fly    72 EPYFDPSTPRNVTALMGKSAYLSCRVRNLANKTVSWIRHRDIHILTVGSYTYTSDQRFQATHHQD 136

  Fly   104 QNTWNLHIKAVSEEDRGGYMCQLNTDPMKSQIGFLDVVIPPDFISEDTSSDVIVPEGSSVRLTCR 168
            ...|.|.||...:.|.|.|.||::|.|::|....|:||:|...|.  ...|:.|.:||::.|||.
  Fly   137 TEDWTLQIKWAQKRDAGMYECQISTQPVRSYFVRLNVVVPTATIL--GGPDLHVDKGSTINLTCT 199

  Fly   169 ARGYPEP--IVTWRREDGNEIVLKDNVGTKTLAPSFRGEV----LKLSKISRNEMGSYLCIASNG 227
            .:..|||  .:.|...:  |::..|:........:.:|:|    |.:......:.|.|.|..||.
  Fly   200 VKFSPEPPAYIFWYHHE--EVINYDSSRGGVSVITEKGDVTTSFLLIQNADLADSGKYSCAPSNA 262

  Fly   228 VPPSV 232
            ...||
  Fly   263 DVASV 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-alpha	NP_001259218.1	IG_like	49..129	CDD:214653	24/80 (30%)
		Ig	51..131	CDD:299845	24/80 (30%)
		I-set	144..240	CDD:254352	23/94 (24%)
		IGc2	159..228	CDD:197706	19/74 (26%)
		Ig	244..337	CDD:299845
		I-set	244..337	CDD:254352
dpr6	NP_001287018.1	V-set	79..174	CDD:284989	28/94 (30%)
		IG_like	80..175	CDD:214653	29/94 (31%)
		IG_like	184..271	CDD:214653	22/85 (26%)
		IGc2	191..262	CDD:197706	18/72 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I11916
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810