DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-alpha and Vsig10

DIOPT Version :9

Sequence 1:	NP_001259218.1	Gene:	DIP-alpha / 31322	FlyBaseID:	FBgn0052791	Length:	554	Species:	Drosophila melanogaster
Sequence 2:	NP_001258265.1	Gene:	Vsig10 / 304529	RGDID:	1565800	Length:	564	Species:	Rattus norvegicus

Alignment Length:	356	Identity:	85/356 - (23%)
Similarity:	138/356 - (38%)	Gaps:	98/356 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 WLKADTKAIQAIHENVITHNPRVTVSHLDQNTWNLHIKAVSEEDRGGYMCQ----LNTDPMKSQI 135
            |::..:...:::.:|            |..|::.|.:  :|:..:|.|.|.    |:....|...
  Rat   192 WIQTHSSVSESLGKN------------LSANSFTLML--MSKNLQGNYTCSATNVLSRRQRKVTT 242

  Fly   136 GFLDVVIPPDFISEDTSSDVIVPEGSSVRLTCR-ARGYPEPIVTWRREDGNEIVLKDNVGTKTLA 199
            ..|....||   |....|..:.||.:::.|||. ..|||:|...|..|.|..:|  .|...:||:
  Rat   243 ELLVYWPPP---SAPQCSAGLSPESANLELTCNWDGGYPDPTFLWTEEPGGVVV--GNSKLQTLS 302

  Fly   200 PSFRGEVLKLSKISRNEMGSYLCIASNGVPPSVSKRISLSIHFHPVIQVPNQLVGA-PL-----G 258
            ||...|..|           :.|:.|:.:.|......        |:|:.:.|:.: |:     |
  Rat   303 PSQLSEGKK-----------FKCVGSHILGPESGASC--------VVQISSPLLASRPMKTCLVG 348

  Fly   259 TDVQIECHVE-ASPKSINYWIKDTGE---MIVTSGKYHVQESSQSMYETKMSMIVRKFQKD-DVG 318
            .||.:.|.|| |:|.:...|:::..:   .|..|.:|.:.:..||     .|:.:....:| |.|
  Rat   349 GDVTLTCQVEGANPPARIQWLRNLTQPETAIQPSSRYVITQQGQS-----SSLTIHNCSQDQDGG 408

  Fly   319 SYRCIAKNSLGEVDSSIRLYEIPGPNRNKNPLNGGGKGG-------------------------- 357
            .|.|.|:|.:|...:.|.|       ..|.|||.||..|
  Rat   409 FYFCRAENPVGVRAADIWL-------SVKEPLNVGGIVGTVVSLLLLGLAIVSGLMLYYSPAFCW 466

  Fly   358 GAGGSL-DADANDILKQKQQVKVTYQPEDEE 387
            .||.:| ..|..|::     |.|..:.|:||
  Rat   467 KAGSTLRGQDMGDVM-----VLVDSEEEEEE 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-alpha	NP_001259218.1	IG_like	49..129	CDD:214653	10/57 (18%)
		Ig	51..131	CDD:299845	10/59 (17%)
		I-set	144..240	CDD:254352	26/96 (27%)
		IGc2	159..228	CDD:197706	21/69 (30%)
		Ig	244..337	CDD:299845	28/103 (27%)
		I-set	244..337	CDD:254352	28/103 (27%)
Vsig10	NP_001258265.1	Ig	60..146	CDD:299845
		IG_like	60..145	CDD:214653
		IG_like	165..246	CDD:214653	11/67 (16%)
		Ig	175..241	CDD:143165	11/62 (18%)
		Ig_3	255..318	CDD:290638	22/75 (29%)
		IG_like	347..429	CDD:214653	25/93 (27%)
		Ig	351..426	CDD:143165	21/79 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12231
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010