DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-alpha and ncam1a

DIOPT Version :9

Sequence 1:NP_001259218.1 Gene:DIP-alpha / 31322 FlyBaseID:FBgn0052791 Length:554 Species:Drosophila melanogaster
Sequence 2:XP_009293555.1 Gene:ncam1a / 30447 ZFINID:ZDB-GENE-990415-31 Length:1010 Species:Danio rerio


Alignment Length:517 Identity:112/517 - (21%)
Similarity:187/517 - (36%) Gaps:154/517 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    16 SCDRNGKML----IHLLLIVSLLEAIGAFQPEFVESISNVSVAVGRDATFTCHVRHLGGY---RV 73
            :|:  |:::    |.|.:|..::..:.:.:..:.|  .|.:..:.:..|..||.   .||   .|
Zfish   185 TCE--GRIMARGEIDLRVIKVIVNVLPSIRTRYTE--LNATADINQAVTLACHA---DGYPEPTV 242

  Fly    74 GWLKADTKAIQAIHENVITHNPRVTVSHLDQNTWNLHIKAVSEEDRGGYMC-QLNTDPMKSQIGF 137
            .|.:.:|:         :..:.:.:   |:::...|.||.|::.|.|.|.| ..|....:|:...
Zfish   243 KWARGNTE---------LESDEKYS---LNEDGSELTIKDVNKLDEGDYKCIARNKAGERSEEVT 295

  Fly   138 LDVVIPP--DFISEDTSSDVIVPEGSSVRLTCRARGYPEPIVTW----------------RRE-- 182
            |:|.:.|  .|:...|:|::    ...:.|||.|.|.|.|.:.|                |.|  
Zfish   296 LNVFVQPKITFLENQTASEL----EEQITLTCEATGDPTPNIIWSFGRRVFTENEQASWTRPEKH 356

  Fly   183 ---DGNEIVLKDNVGTKTLAPSFRGEVLKLSKISRNEMGSYLCIASNGVPPSVSKRISLSIHFHP 244
               |||.:|..|          .|...|.|..:...:.|.|||.|.|.:...: :.:.|.:.:.|
Zfish   357 KSLDGNVVVRSD----------ARVSSLTLKYVQFTDAGQYLCTARNSIGQDI-QSMYLEVRYAP 410

  Fly   245 VIQVPNQLVGAPLGTDVQIECHVEASPKSINYWIKDTGEMIVTSGKYHVQESSQSMYET-KMSMI 308
            .||.| |.|....|....|.|...|.|.:...|.:| |:.:.::...:|:     :|.| .:|.:
Zfish   411 KIQGP-QAVFTWEGNPANITCEALAHPGASVLWFRD-GQQLPSANTTNVK-----IYNTPTVSFL 468

  Fly   309 -VRKFQKDDVGSYRCIAKNSLGEVDSSIRLYEIPGPN----------------RNKNPLNGGGKG 356
             |....::|.|||.|.|.|.:|.......|.:...|:                ..:.|.:.||. 
Zfish   469 EVTPDSQNDFGSYNCTATNVIGTESKEFILVQADVPSAPSIERVEPYSSTAMIEFEEPASSGGV- 532

  Fly   357 GGAGGSLDADANDILKQKQQVKVT--------YQPED-----------EELQYGSVEDFEAEG-G 401
                        .:||.|.:.::.        |:.||           .|..| .|:.....| |
Zfish   533 ------------PVLKYKAEWRIAGQDWTDREYELEDGLNLITIVGLKPETTY-EVKISAINGKG 584

  Fly   402 EGGGLTP-------------LSPHVYYTSGNKPAT--------------HKPGNSGGNQHLH 436
            ||....|             :||.   |..:.|.|              .||.::|....:|
Zfish   585 EGESSAPESFKTQPVRLPFRMSPE---TPTSIPPTTADIKGEPNPPKLEAKPQSTGNEMKVH 643

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-alphaNP_001259218.1 IG_like 49..129 CDD:214653 19/83 (23%)
Ig 51..131 CDD:299845 18/83 (22%)
I-set 144..240 CDD:254352 29/118 (25%)
IGc2 159..228 CDD:197706 24/89 (27%)
Ig 244..337 CDD:299845 27/94 (29%)
I-set 244..337 CDD:254352 27/94 (29%)
ncam1aXP_009293555.1 Ig 20..112 CDD:299845
I-set 21..111 CDD:254352
IG_like 121..200 CDD:214653 4/16 (25%)
IGc2 128..189 CDD:197706 1/5 (20%)
Ig 208..301 CDD:299845 23/109 (21%)
IG_like 219..298 CDD:214653 21/93 (23%)
Ig 300..406 CDD:299845 29/120 (24%)
IG_like 308..406 CDD:214653 27/112 (24%)
ig 413..498 CDD:278476 25/91 (27%)
IG_like 415..498 CDD:214653 24/89 (27%)
fn3 505..589 CDD:278470 16/97 (16%)
FN3 624..715 CDD:238020 4/20 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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