DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-alpha and Dscam4

DIOPT Version :9

Sequence 1:NP_001259218.1 Gene:DIP-alpha / 31322 FlyBaseID:FBgn0052791 Length:554 Species:Drosophila melanogaster
Sequence 2:NP_001261571.1 Gene:Dscam4 / 2769008 FlyBaseID:FBgn0263219 Length:1935 Species:Drosophila melanogaster


Alignment Length:452 Identity:101/452 - (22%)
Similarity:172/452 - (38%) Gaps:119/452 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MPVSAKRLLRNFQFTSCDRNGKMLIHLLLIVSLLEAIGAF-----QPEFVESISNVSVAV----- 55
            :|::.::...|        ||.::|..|   ..||..|.:     ..:...|..||.:.|     
  Fly   559 LPINRRQRAYN--------NGTLIIEQL---QRLEDAGTYTCMAQNKQKQTSRRNVEIQVLVPPK 612

  Fly    56 -------------GRDATFTCHVRHLGGYRVG--WLKADTKAIQAIHENVITHNPRVTVSHLDQN 105
                         |..|..:|.:.. |...|.  |.:.....|...:|         ....||:.
  Fly   613 IMPIQAMTNMLREGMRAAISCQILE-GDLPVSFRWERNGKPLIGTGNE---------VFRRLDEY 667

  Fly   106 TWNLHIKAVSEEDRGGYMC--------QLNTDPMKSQIGFLDVVIPPDFISE--DTSSDVIVPEG 160
            :.:|.|:.:|.:..|.|.|        :..|.|       |.|.:||.:|.|  |:|:..    |
  Fly   668 SASLVIEHISSDHSGNYTCIASNVAGTERFTVP-------LTVNVPPKWILEPKDSSAQA----G 721

  Fly   161 SSVRLTCRARGYPEPIVTWRREDG---NEIVLKDNVGTKTLAPSFRGEVLKLSKISRNEMGSYLC 222
            :.|.|.|::.|||.|.:||::..|   .|  .||.:...|: ..|....:...|||:...|.:||
  Fly   722 ADVLLHCQSSGYPTPTITWKKAIGPTPGE--YKDFLYEPTV-QLFPNGTIFFKKISKESQGHFLC 783

  Fly   223 IASNGVPPSVSKRISLSIHFHPVIQVPNQLVGAPLGTDVQIECHVEA-SPKSINYWIKDTGEMIV 286
            .|.|.:...|||.|.|.::.....|...:.:....|..|.::|:|:. :|....:.|:.|     
  Fly   784 EAKNNIGSGVSKVIFLKVNVPAHFQTKTKQISVAKGKQVHVQCNVQGDNPIDFKWKIQAT----- 843

  Fly   287 TSGKYHVQESSQSMYETKMSMI---------VRKFQKDDVGSYRCIAKNSLGEVDSSIRLYEIPG 342
               :.::.||..|.|..:..::         :....:.|.|.|.|.|.|:.|:.:.||:|.....
  Fly   844 ---QQYLDESLDSRYTIRDQVLDDGMVSELGISHTYRQDTGIYICQASNAFGQDEMSIQLIVQEV 905

  Fly   343 PNRNKN-PLNGGGKGGGAGGSLDADANDILKQKQQVKVTY-QP-------EDEELQYGSVED 395
            |.:.|| .:|.                   :|.:.:::|: ||       |:..:.|..:.|
  Fly   906 PEQPKNLRINS-------------------QQSRSLQLTWSQPFAGNSPIEEYHIYYKQISD 948

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-alphaNP_001259218.1 IG_like 49..129 CDD:214653 19/107 (18%)
Ig 51..131 CDD:299845 19/107 (18%)
I-set 144..240 CDD:254352 34/100 (34%)
IGc2 159..228 CDD:197706 24/71 (34%)
Ig 244..337 CDD:299845 21/102 (21%)
I-set 244..337 CDD:254352 21/102 (21%)
Dscam4NP_001261571.1 Ig 31..124 CDD:416386
Ig strand A 32..35 CDD:409353
Ig strand A' 41..45 CDD:409353
Ig strand B 48..57 CDD:409353
Ig strand D 75..78 CDD:409353
Ig strand E 83..88 CDD:409353
Ig strand F 101..109 CDD:409353
Ig strand G 112..124 CDD:409353
Ig 235..326 CDD:416386
Ig strand A 235..238 CDD:409353
Ig strand A' 244..248 CDD:409353
Ig strand B 251..258 CDD:409353
Ig strand C 266..271 CDD:409353
Ig strand C' 276..279 CDD:409353
Ig strand D 285..289 CDD:409353
Ig strand E 292..298 CDD:409353
Ig strand F 305..313 CDD:409353
Ig strand G 316..326 CDD:409353
IgC2_3_Dscam 329..417 CDD:409549
Ig strand B 347..351 CDD:409549
Ig strand C 360..364 CDD:409549
Ig strand E 383..387 CDD:409549
Ig strand F 397..402 CDD:409549
Ig strand G 410..413 CDD:409549
IgI_4_Dscam 422..516 CDD:409548
Ig strand B 439..443 CDD:409548
Ig strand C 452..456 CDD:409548
Ig strand E 482..486 CDD:409548
Ig strand F 496..501 CDD:409548
Ig strand G 509..512 CDD:409548
IgI_5_Dscam 520..607 CDD:409550 12/58 (21%)
Ig strand B 536..540 CDD:409550
Ig strand C 549..553 CDD:409550
Ig strand E 571..575 CDD:409550 1/3 (33%)
Ig strand F 586..591 CDD:409550 0/4 (0%)
Ig strand G 600..603 CDD:409550 0/2 (0%)
Ig 610..703 CDD:416386 19/109 (17%)
Ig strand A 611..613 CDD:409353 0/1 (0%)
Ig strand A' 620..624 CDD:409353 0/3 (0%)
Ig strand B 627..636 CDD:409353 2/8 (25%)
Ig strand C 641..648 CDD:409353 2/6 (33%)
Ig strand C' 650..652 CDD:409353 0/1 (0%)
Ig strand D 659..664 CDD:409353 1/13 (8%)
Ig strand E 668..675 CDD:409353 2/6 (33%)
Ig strand F 682..690 CDD:409353 3/7 (43%)
Ig strand G 693..702 CDD:409353 2/15 (13%)
IgI_7_Dscam 706..801 CDD:409546 35/101 (35%)
Ig strand B 724..728 CDD:409546 2/3 (67%)
Ig strand C 737..741 CDD:409546 1/3 (33%)
Ig strand E 766..770 CDD:409546 0/3 (0%)
Ig strand F 780..785 CDD:409546 2/4 (50%)
Ig strand G 794..797 CDD:409546 2/2 (100%)
Ig 818..904 CDD:416386 21/93 (23%)
putative Ig strand B 820..827 CDD:409353 1/6 (17%)
putative Ig strand C 835..841 CDD:409353 0/5 (0%)
putative Ig strand C' 853..856 CDD:409353 1/2 (50%)
putative Ig strand D 862..866 CDD:409353 0/3 (0%)
putative Ig strand E 868..874 CDD:409353 0/5 (0%)
putative Ig strand F 881..889 CDD:409353 4/7 (57%)
putative Ig strand G 892..902 CDD:409353 4/9 (44%)
FN3 906..999 CDD:238020 11/62 (18%)
FN3 1006..1110 CDD:238020
fn3 1117..1203 CDD:394996
FN3 1215..1307 CDD:238020
Ig <1334..1401 CDD:416386
Ig strand C 1345..1349 CDD:409353
Ig strand D 1363..1366 CDD:409353
Ig strand E 1367..1372 CDD:409353
Ig strand F 1380..1388 CDD:409353
Ig strand G 1394..1401 CDD:409353
FN3 1405..1494 CDD:238020
FN3 1499..1580 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.810

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