DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-alpha and dpr7

DIOPT Version :9

Sequence 1:	NP_001259218.1	Gene:	DIP-alpha / 31322	FlyBaseID:	FBgn0052791	Length:	554	Species:	Drosophila melanogaster
Sequence 2:	NP_001096850.2	Gene:	dpr7 / 2768865	FlyBaseID:	FBgn0053481	Length:	312	Species:	Drosophila melanogaster

Alignment Length:	223	Identity:	57/223 - (25%)
Similarity:	91/223 - (40%)	Gaps:	47/223 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 FVESIS--NVSVAVGRDATFTCHVRHLGGYRVGWLKADTKAIQAIHENVITH--NPRVTVSH-LD 103
            |.:.||  |||..|...|...|.|::.|...|.|::  .:.:..:..|:.|:  :.|.:|.| ..
  Fly    52 FFDDISPRNVSAVVDEIAILRCRVKNKGNRTVSWMR--KRDLHILTTNIYTYTGDQRFSVIHPPG 114

  Fly   104 QNTWNLHIKAVSEEDRGGYMCQLNTDPMKSQIGFLDVVIPPDFISEDT----------------S 152
            ...|:|.|......|.|.|.||:||:|..:....|.|:...||....|                |
  Fly   115 SEDWDLKIDYAQPRDSGVYECQVNTEPKINLAICLQVIADNDFQDLKTKKRFYDTKSARAKILGS 179

  Fly   153 SDVIVPEGSSVRLTCRARGYPEPIVTWRREDGNEIV-------------LKDNVGTKTLAPSFRG 204
            :::.|...|::.|.|....: .|.|.|..  |:.:|             .|.:|||.:.
  Fly   180 TEIHVKRDSTIALACSVNIH-APSVIWYH--GSSVVDFDSLRGGISLETEKTDVGTTSR------ 235

  Fly   205 EVLKLSKISRNEMGSYLCIASNGVPPSV 232
              |.|::.|..:.|:|.|:.:..:|.||
  Fly   236 --LMLTRASLRDSGNYTCVPNGAIPASV 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-alpha	NP_001259218.1	IG_like	49..129	CDD:214653	25/84 (30%)
		Ig	51..131	CDD:299845	24/82 (29%)
		I-set	144..240	CDD:254352	26/118 (22%)
		IGc2	159..228	CDD:197706	18/81 (22%)
		Ig	244..337	CDD:299845
		I-set	244..337	CDD:254352
dpr7	NP_001096850.2	V-set	56..145	CDD:284989	28/90 (31%)
		IG_like	58..140	CDD:214653	24/83 (29%)
		IG_like	179..265	CDD:214653	23/94 (24%)
		Ig	187..257	CDD:299845	18/80 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I11916
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.910