DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-alpha and zig-3

DIOPT Version :9

Sequence 1:	NP_001259218.1	Gene:	DIP-alpha / 31322	FlyBaseID:	FBgn0052791	Length:	554	Species:	Drosophila melanogaster
Sequence 2:	NP_509336.1	Gene:	zig-3 / 192088	WormBaseID:	WBGene00006980	Length:	251	Species:	Caenorhabditis elegans

Alignment Length:	204	Identity:	52/204 - (25%)
Similarity:	88/204 - (43%)	Gaps:	30/204 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   154 DVIVPEGSSVRLTCRARGYPEPIVTWRREDGNEIV--LKDNVGTKTL---APSFRGEVL----KL 209
            |..|..|.||.|.|.....|..::.|.: ||..|.  .:.||..|.|   .|:....::    ::
Worm    52 DNTVSTGESVTLRCDVLSTPTGVIYWEK-DGQRIQGDKELNVFEKVLNAMGPTVESGIITSSYQI 115

  Fly   210 SKISRNEMGSYLCIASNGVPPSVSKRISLSIHFHPVIQVPNQLVGAP---LGTDVQIECHVEA-- 269
            ...:.:.:|||.|:|:|| ..:|.....:|:. ...::..:....||   :.|:.:.|....|
Worm   116 PCANLHHIGSYKCVATNG-HDTVESSAKISVE-GQTVKCKSTRRSAPVITMSTESRFELQDNAAT 178

  Fly   270 ----SPKSINY-WIKDTGEMIVTSGKYHVQESSQSMYETKMSMIVRKFQKDDVGSYRCIAKNSLG 329
                :.:..|: |:.:..::...||:|.:..|.        .:::||.|..|:|||.|||.|..|
Worm   179 LICRADRRANWNWMFEDKKIDFDSGRYELLPSG--------DLLIRKIQWSDMGSYFCIAHNKYG 235

  Fly   330 EVDSSIRLY 338
            |......||
Worm   236 ESRGETFLY 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-alpha	NP_001259218.1	IG_like	49..129	CDD:214653
		Ig	51..131	CDD:299845
		I-set	144..240	CDD:254352	25/94 (27%)
		IGc2	159..228	CDD:197706	21/77 (27%)
		Ig	244..337	CDD:299845	24/102 (24%)
		I-set	244..337	CDD:254352	24/102 (24%)
zig-3	NP_509336.1	I-set	45..145	CDD:254352	25/94 (27%)
		Ig	61..142	CDD:143165	21/82 (26%)
		IG_like	177..244	CDD:214653	19/74 (26%)
		Ig	<191..237	CDD:299845	17/53 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900