DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-alpha and zig-8

DIOPT Version :9

Sequence 1:	NP_001259218.1	Gene:	DIP-alpha / 31322	FlyBaseID:	FBgn0052791	Length:	554	Species:	Drosophila melanogaster
Sequence 2:	NP_499714.1	Gene:	zig-8 / 176732	WormBaseID:	WBGene00006985	Length:	268	Species:	Caenorhabditis elegans

Alignment Length:	193	Identity:	47/193 - (24%)
Similarity:	78/193 - (40%)	Gaps:	18/193 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 VESISN--VSVAVGRDATFTCHVRHLGGYRVGWLKADTKAIQAIHENVITHNPRVTVSHLDQNTW 107
            ||:.|.  |:|.....|...|.|.....:.:.|.:....|:........|.:||..||....|.|
Worm    37 VENPSQTIVNVVAENPAYLHCSVPPDAEHEIAWTRVSDGALLTAGNRTFTRDPRWQVSKKSANIW 101

  Fly   108 NLHIKAVSEEDRGGYMCQLNTDPMKSQIGFLDVVIP----PDFISEDTSSDVIVPEGSSVRLTC- 167
            .|:::...::|.|.|:|::|.........:|.|:.|    |..:.:.::..:....|..|.|.|
Worm   102 VLNLRRAEQQDSGCYLCEINDKHNTVYAVYLKVLEPPLPSPSSLQKKSTKLMANMSGDEVVLNCT 166

  Fly   168 -RARGYPEPI--VTWRREDGNEIVLKDNVGTKTLAPSFRG-----EVLKLSKISRNEMGSYLC 222
             .:....|.:  |.|.| |||.|...|.  .|.:....|.     |.:::.|.:..:.|:|.|
Worm   167 VTSTDKDEEVLDVVWTR-DGNTINFNDT--EKYILKVKRDAGVVIETMRIRKATMEDDGNYAC 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-alpha	NP_001259218.1	IG_like	49..129	CDD:214653	21/81 (26%)
		Ig	51..131	CDD:299845	20/79 (25%)
		I-set	144..240	CDD:254352	21/88 (24%)
		IGc2	159..228	CDD:197706	20/73 (27%)
		Ig	244..337	CDD:299845
		I-set	244..337	CDD:254352
zig-8	NP_499714.1	IG_like	55..134	CDD:214653	18/78 (23%)
		Ig	55..129	CDD:143165	17/73 (23%)
		ig	158..229	CDD:278476	20/72 (28%)
		IG_like	158..227	CDD:214653	20/72 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810