Protein Alignment DIP-alpha and rig-5

DIOPT Version :10

• Sequence 1: NP_726871.1
• Gene: DIP-alpha / 31322
• FlyBaseID: FBgn0052791
• Length: 554
• Species: Drosophila melanogaster
• Sequence 2: NP_001251131.1
• Gene: rig-5 / 172791
• WormBaseID: WBGene00004372
• Length: 482
• Species: Caenorhabditis elegans
• Alignment Length: 419
• Identity: 139/419 - (33%)
• Similarity: 202/419 - (48%)
• Gaps: 43/419 - (10%)

  Fly    22 KMLIHLLLIVSLL---EAIGAFQPEFVE--SISNVSVAVGRDATFTCHVRHLGGYRVGWLKADT- 80
            ||.:..||...||   :|.....|..::  |:|:....:|:|..|||.|..||.:.|.::|||:
 Worm    60 KMYLFALLCGVLLVFKQACSRGAPPTIQQPSMSSAVALLGQDVDFTCIVNDLGSHMVAFVKADSP 124

  Fly    81 KAIQAIHENVITH------NPRVTVSHLDQNTWNLHIKAVSEEDRGGYMCQLNTDPMKSQIGFLD 139
            ..:.:..|.|...      .||:...|   |.|.|.||.|.|.|||.|.||:||:|:....|.||
 Worm   125 PRLLSFDEKVFRRRNKYELKPRIGDLH---NEWVLTIKNVQESDRGNYSCQINTEPITLSTGELD 186

  Fly   140 VVIPPDFISEDTSSDVIVPEGSSVRLTCRARGYPEPIVTWRREDGNEIVLKDNVGTKTLAPSFRG 204
            |.:|| .:|..|.:.|.|.||::|.|||:|.|.|.|.|.|||:|..  :::.|..|...|..|.|
 Worm   187 VKVPP-VVSRSTPAAVEVREGNNVSLTCKADGNPTPTVIWRRQDRQ--IIRYNGATGFGASVFHG 248

  Fly   205 EVLKLSKISRNEMGSYLCIASNGVPPSVSKRISLSIHFHPVIQVPNQLVGAPLGTDVQIECHVEA 269
            .||.|:|:||..|..|||:||||:||..|..:.|.:.|.|::|..::.|.|.:|:..::.|..||
 Worm   249 PVLHLTKVSRKHMSEYLCVASNGIPPDESWTVKLLVTFPPLVQAQSETVQASVGSMARMVCTTEA 313

  Fly   270 SPKSINYWIKDTGEMIVTSGKYHVQESSQSMYETKMSMIVRKFQKDDVGSYRCIAKNSLGEVDSS 334
            .|:....|.|| ||.:..|....:..:....|.:...:.:|..|....|.|||:|||..|...|.
 Worm   314 WPRPEMGWEKD-GEPVYESNNVAMTHTVSGQYHSVHILEIRNVQSSHFGVYRCVAKNDNGIHHSQ 377

  Fly   335 IRLYEIPGPNRNKNPLNGGGKGGGAGGSLDADANDILKQKQQVKVTYQPEDEELQYGSVEDFEAE 399
            :.|.:|...:...:.|...|.|...|.|.|.:|::              |::.|: ....|.|.|
 Worm   378 VTLNQISHNHFTNSNLIPEGSGMPRGYSEDDEADE--------------EEDNLE-NQKNDSEEE 427

  Fly   400 GGEGGGLTPLSPHVY-----YTSGNKPAT 423
            ..:    :|.....|     :.|.|.|.|
 Worm   428 DSQ----SPPQLEFYSQARRHESRNAPTT 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DIP-alpha	NP_726871.1	IG_like	49..129	CDD:214653	32/86 (37%)
		Ig strand B	59..63	CDD:409353	1/3 (33%)
		Ig strand C	72..76	CDD:409353	1/3 (33%)
		Ig strand E	103..111	CDD:409353	3/7 (43%)
		Ig	152..240	CDD:472250	40/87 (46%)
		Ig strand B	163..167	CDD:409275	2/3 (67%)
		Ig strand C	176..180	CDD:409275	1/3 (33%)
		Ig strand E	205..209	CDD:409275	2/3 (67%)
		Ig strand F	219..224	CDD:409275	3/4 (75%)
		Ig strand G	233..236	CDD:409275	1/2 (50%)
		Ig	244..337	CDD:472250	27/92 (29%)
		Ig strand B	261..265	CDD:409353	0/3 (0%)
		Ig strand C	274..278	CDD:409353	0/3 (0%)
		Ig strand E	305..309	CDD:409353	0/3 (0%)
		Ig strand F	319..324	CDD:409353	3/4 (75%)
		Ig strand G	332..335	CDD:409353	1/2 (50%)
rig-5	NP_001251131.1	IG_like	92..189	CDD:214653	38/99 (38%)
		Ig strand B	102..106	CDD:409353	1/3 (33%)
		Ig strand C	118..122	CDD:409353	1/3 (33%)
		Ig strand E	154..158	CDD:409353	2/3 (67%)
		Ig strand F	168..173	CDD:409353	2/4 (50%)
		Ig_3	190..270	CDD:464046	37/82 (45%)
		Ig_3	287..369	CDD:464046	23/82 (28%)