DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-alpha and ncam1b

DIOPT Version :9

Sequence 1:NP_001259218.1 Gene:DIP-alpha / 31322 FlyBaseID:FBgn0052791 Length:554 Species:Drosophila melanogaster
Sequence 2:XP_005157462.1 Gene:ncam1b / 114442 ZFINID:ZDB-GENE-010822-2 Length:1055 Species:Danio rerio


Alignment Length:454 Identity:94/454 - (20%)
Similarity:156/454 - (34%) Gaps:102/454 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    15 TSCDRNGKMLIHLLLIVSLLEAIGAFQPEFVESISNVSVAVGRDATFTCHVRHLGGYRVGWLKAD 79
            :|.|::.:..::|.:...:.........||.|         |.:|...|.|.......|.|....
Zfish    97 SSGDQDAEATVNLKIYQKITFTNVPSPQEFTE---------GDNAIIVCDVISSPPPTVLWKYKG 152

  Fly    80 TKAIQAIHENVITHNPRVTVSHLDQNTWNLHIKAVSEEDRGGYMCQLNTDPMKSQIGF--LDVVI 142
            .|         |..:..|....|..|  :|.|:.:.:.|.|.|.|: .....:.::.|  :.||:
Zfish   153 AK---------IQFDKDVRFKTLSNN--HLQIRGIRKTDEGVYTCE-GRIKARGEVDFRSIKVVV 205

  Fly   143 P--PDFISEDTSSDVIVPEGSSVRLTCRARGYPEPIVTWRR-----EDGNEIVLKDNVGTKTLAP 200
            .  |........::.....|.|..|.|...|:|||||||||     |.||:....::....|   
Zfish   206 NVLPTIRIRQAETNATADMGFSTLLACDPDGFPEPIVTWRRNNAPLESGNKYSFNEDGSEMT--- 267

  Fly   201 SFRGEVLKLSKISRNEMGSYLCIASNGVPPSVSKRISLSIHFHPVIQVPNQLVGAPLGTDVQIEC 265
                 ||.::|:   :.|.|.|||.|....| .:.:||.:...|.|..........:...|.:.|
Zfish   268 -----VLDVTKL---DEGDYTCIAKNKAGES-EQELSLKVFVQPKITYLESQTTTEMDEQVTLTC 323

  Fly   266 HVEASPKSINYWIKDTGEMIVTSGKYHVQESSQSMY---------------------ETKMSMIV 309
            .....|.....|  ..|..:.|.|:   ||..:.:|                     :.::|.:.
Zfish   324 EATGDPTPTITW--SFGTRVFTEGE---QEQQKRIYQASWTRPEQHKGPDGEVLVRSDARVSSLT 383

  Fly   310 RKF-QKDDVGSYRCIAKNSLGE--------------VDSSIRLYEIPGPNRNKNPLNGGGKGGGA 359
            .|: |..|.|.|.|.|:|::||              :..|:.:|...|     ||.|        
Zfish   384 LKYPQYTDAGQYLCTARNAIGETVQPVSLEVRYAPKILGSVAVYTWEG-----NPAN-------- 435

  Fly   360 GGSLDADANDILKQKQQVKVTYQPEDEELQYGSVEDFEAEGGEGGGLTPLSPHVYYTSGNKPAT 423
                  .:.::|.....|.:|:..:..:|...:..:.:...........::|......||...|
Zfish   436 ------ISCEVLAHPSDVSITWLRDGFQLPNANTSNIKIHNTPSASYLEVNPESQSDFGNYNCT 493

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-alphaNP_001259218.1 IG_like 49..129 CDD:214653 17/79 (22%)
Ig 51..131 CDD:299845 17/79 (22%)
I-set 144..240 CDD:254352 31/100 (31%)
IGc2 159..228 CDD:197706 27/73 (37%)
Ig 244..337 CDD:299845 24/128 (19%)
I-set 244..337 CDD:254352 24/128 (19%)
ncam1bXP_005157462.1 Ig 20..112 CDD:299845 3/14 (21%)
I-set 21..111 CDD:254352 3/13 (23%)
IG_like 121..205 CDD:214653 22/104 (21%)
IGc2 128..189 CDD:197706 18/81 (22%)
Ig 208..301 CDD:299845 31/104 (30%)
I-set 212..298 CDD:254352 30/97 (31%)
I-set 298..414 CDD:254352 23/120 (19%)
Ig 300..414 CDD:299845 23/118 (19%)
IG_like 426..505 CDD:214653 13/87 (15%)
Ig 434..505 CDD:143165 9/74 (12%)
FN3 513..606 CDD:238020
FN3 629..720 CDD:238020
Chorion_3 <815..1019 CDD:253174
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR12231
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
22.010

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