Protein Alignment DIP-alpha and negr1

DIOPT Version :10

• Sequence 1: NP_726871.1
• Gene: DIP-alpha / 31322
• FlyBaseID: FBgn0052791
• Length: 554
• Species: Drosophila melanogaster
• Sequence 2: XP_031755650.1
• Gene: negr1 / 100127726
• XenbaseID: XB-GENE-987949
• Length: 388
• Species: Xenopus tropicalis
• Alignment Length: 325
• Identity: 90/325 - (27%)
• Similarity: 149/325 - (45%)
• Gaps: 55/325 - (16%)

  Fly    47 SISNVSVAVGRDATFTCHVRHLGGYRVGWLKADTKAIQAIHENVI-------THNPRVTVSHLDQ 104
            ::.|:.|..|..|...|.:.. |..:..||.         ..::|       :.:|||:::...:
 Frog    45 AVDNLVVRQGETAMLRCFLEE-GASKGAWLN---------RSSIIFAGGDKWSVDPRVSIATSSK 99

  Fly   105 NTWNLHIKAVSEEDRGGYMCQLNTD--PMKSQIGFLDVVIPPDFISEDTSSDVIVPEGSSVRLTC 167
            ..::|.|:.|...|.|.|.|.:.|:  |...|: .|.|.:.|...  |.|||:.|.||::|.|.|
 Frog   100 QEYSLRIQKVDVSDDGPYTCSVQTEHSPRTLQV-HLTVHVSPKIY--DISSDMTVNEGTNVSLIC 161

  Fly   168 RARGYPEPIVTWRREDGNEIVLKDNVGTKTLAPSFR----GEVLKLSKISRNEMGSYLCIASNGV 228
            .|.|.|||.::||.                ::||.:    |:.|.:..|:|::.|.|.|.|.|.|
 Frog   162 LATGKPEPSISWRH----------------ISPSAKQFGSGQYLDIYGITRDQAGDYECSAENDV 210

  Fly   229 P-PSVSKRISLSIHFHPVIQ--VPNQLVGAPLGTDVQIECHVEASPKSINYWIKDTGEMIVTSGK 290
            . |.| |::.::::|.|.|.  .|   .|..||....|.|...|.|..:..|.|  ||..:|:|:
 Frog   211 SFPDV-KKVKVTVNFAPTILEITP---TGVSLGRTGLIRCETAAVPAPVFEWYK--GEKKLTNGQ 269

  Fly   291 YHVQESSQSMYETKMSMIVRKFQKDDVGSYRCIAKNSLGEVDSSIRLYEIPGPNRNKNPLNGGGK 355
            ..::..:   |.|:..:.|....::..|:|.|:|.|.||..::|:.|.:|..|: ..:|:....|
 Frog   270 RGIRIQN---YNTRSILTVSNVTEEHFGNYTCVAVNKLGTSNASLPLNQIIEPS-TTSPVTSSAK 330

  Fly   356  355
             Frog   331  330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DIP-alpha	NP_726871.1	IG_like	49..129	CDD:214653	19/86 (22%)
		Ig strand B	59..63	CDD:409353	1/3 (33%)
		Ig strand C	72..76	CDD:409353	0/3 (0%)
		Ig strand E	103..111	CDD:409353	1/7 (14%)
		Ig	152..240	CDD:472250	31/92 (34%)
		Ig strand B	163..167	CDD:409275	2/3 (67%)
		Ig strand C	176..180	CDD:409275	0/3 (0%)
		Ig strand E	205..209	CDD:409275	1/3 (33%)
		Ig strand F	219..224	CDD:409275	2/4 (50%)
		Ig strand G	233..236	CDD:409275	1/2 (50%)
		Ig	244..337	CDD:472250	27/94 (29%)
		Ig strand B	261..265	CDD:409353	1/3 (33%)
		Ig strand C	274..278	CDD:409353	0/3 (0%)
		Ig strand E	305..309	CDD:409353	0/3 (0%)
		Ig strand F	319..324	CDD:409353	2/4 (50%)
		Ig strand G	332..335	CDD:409353	0/2 (0%)
negr1	XP_031755650.1	Ig	44..136	CDD:472250	23/101 (23%)
		Ig strand B	57..61	CDD:409353	1/3 (33%)
		Ig strand C	70..73	CDD:409353	0/2 (0%)
		Ig strand E	102..106	CDD:409353	1/3 (33%)
		Ig strand F	116..121	CDD:409353	2/4 (50%)
		Ig strand G	129..132	CDD:409353	0/2 (0%)
		Ig	146..222	CDD:472250	31/92 (34%)
		Ig strand B	157..161	CDD:409301	2/3 (67%)
		Ig strand C	170..174	CDD:409301	0/3 (0%)
		Ig strand E	187..191	CDD:409301	1/3 (33%)
		Ig strand F	201..206	CDD:409301	2/4 (50%)
		Ig strand G	215..218	CDD:409301	2/3 (67%)
		Ig_3	226..302	CDD:464046	23/83 (28%)