DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-alpha and igsf9

DIOPT Version :9

Sequence 1:	NP_001259218.1	Gene:	DIP-alpha / 31322	FlyBaseID:	FBgn0052791	Length:	554	Species:	Drosophila melanogaster
Sequence 2:	NP_001090640.1	Gene:	igsf9 / 100036605	XenbaseID:	XB-GENE-989817	Length:	1423	Species:	Xenopus tropicalis

Alignment Length:	329	Identity:	80/329 - (24%)
Similarity:	137/329 - (41%)	Gaps:	36/329 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 IHLLLIVSLLEAIGAFQPEFVESISNVSVA-VGRDATFTCHVRHLGG-----YRVGWLKADTKAI 83
            :|..|.:::|..........:.|.|...|. ||......|.:.|...     |.:.|::..  .:
Frog     1 MHWCLCINVLILFSCCINGAIRSDSQTVVGRVGESTVLGCSLLHQDAGRPPLYVIEWVRFG--FM 63

  Fly    84 QAIHENVITHNPRVTVSHLD----QNTWNLHIKAVSEEDRGGYMCQ-LNTDPMKSQIGF------ 137
            ..|......::|||...:|.    :...:|||:::..||:|.|.|: |..|....:..|
Frog    64 LPIFIKFGLYSPRVDPQYLGRTRIEEGASLHIESLRSEDQGWYECRVLFLDRHHGEEDFQNGTWV 128

  Fly   138 -LDVVIPPDFISEDTSSDVIVPEGSSVRLTCRARGYPEPIVTWRREDGNEIVLKDNVGTKTLAPS 201
             |.|..||.| .|...:.|.|..|.::.|||.|.|.|:|:|||:| ||..:...|.|.....:.|
Frog   129 HLTVNSPPSF-RETPPTYVEVRVGDTLTLTCVAYGNPQPVVTWKR-DGVTLESGDKVQASNGSLS 191

  Fly   202 FRGEVLKLSKISRNEMGSYLCIASNGVPPSVSKRISLSIHFHPVIQVPNQLVGAPLGTDVQIECH 266
            ..|       :.|...|.|.|.|.:. ...|:....:.:...|:|.||.:.....:..|..:.|.
Frog   192 IVG-------VERGNAGVYTCHAFSD-EGEVTHTSRVLVQGPPIIVVPPENTTVNVSQDAFLTCQ 248

  Fly   267 VEASPKSINY-WIKDTGEMIVTSGKYHVQESSQSMYETKMSMIVRKFQKDDVGSYRCIAKNSLGE 330
            .||.|.::.| |.:.:..:.:.:   .:|...:.:.:.  |.::::...:|.|.|.||..|.:.:
Frog   249 AEAYPANLTYTWFQGSNNVFLLN---RLQPRVRILVDG--SFLIQRVTPEDAGKYTCIPSNGMWK 308

  Fly   331 VDSS 334
            ..|:
Frog   309 SPSA 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-alpha	NP_001259218.1	IG_like	49..129	CDD:214653	22/90 (24%)
		Ig	51..131	CDD:299845	22/90 (24%)
		I-set	144..240	CDD:254352	29/95 (31%)
		IGc2	159..228	CDD:197706	23/68 (34%)
		Ig	244..337	CDD:299845	20/92 (22%)
		I-set	244..337	CDD:254352	20/92 (22%)
igsf9	NP_001090640.1	Ig	25..132	CDD:299845	25/108 (23%)
		IG_like	25..110	CDD:214653	21/86 (24%)
		I-set	136..222	CDD:254352	29/95 (31%)
		IGc2	151..212	CDD:197706	23/69 (33%)
		Ig_2	226..318	CDD:290606	20/92 (22%)
		I-set	226..318	CDD:254352	20/92 (22%)
		IG_like	328..407	CDD:214653
		Ig	340..402	CDD:299845
		IG_like	431..502	CDD:214653
		Ig	439..502	CDD:299845
		FN3	507..601	CDD:238020
		FN3	624..714	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12231
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100