DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10802 and Aarsd1

DIOPT Version :9

Sequence 1:	NP_570062.1	Gene:	CG10802 / 31318	FlyBaseID:	FBgn0029664	Length:	436	Species:	Drosophila melanogaster
Sequence 2:	NP_659078.1	Gene:	Aarsd1 / 69684	MGIID:	1916934	Length:	412	Species:	Mus musculus

Alignment Length:	422	Identity:	188/422 - (44%)
Similarity:	240/422 - (56%)	Gaps:	29/422 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVFKCQEDSFLKEFKTKIVSSEFATLDWTDPSGKVEKLKGFNVICEDTILFPEGGGQPCDYGTLG 65
            |.|.||.||:.:||.|.:||...|.|......||.|.|.||:|:.|||:|||||||||.|.||:.
Mouse     1 MAFLCQRDSYAREFTTTVVSCSPAELQTDASGGKKEVLSGFHVVLEDTLLFPEGGGQPDDRGTIN 65

  Fly    66 GFPVKNVQRKGSTAVHFVESPTSFEQDAEVLLTLDYQRRLDHMQQHSGQHLITALFDREFKYDTT 130
            ...|..|.|:|:.|.||.|||.|  ..::|.:.:|::||.||||||||||||||:.|..|...||
Mouse    66 DISVLRVTRRGAQADHFTESPLS--PGSQVQVRVDWERRFDHMQQHSGQHLITAVADLLFGLKTT 128

  Fly   131 SWSLGSTVSYIQLSTPHLISRESLDLIERQANDLIREGREVTV---LLVDPEVAQEFQDARAPRG 192
            ||.||...|.|:|.:|. ::.|.:..||:..|..||:...|:|   .|.||||.|    .|. ||
Mouse   129 SWELGRLRSVIELDSPS-VTAEQVAAIEQSVNQKIRDRLPVSVRELSLDDPEVEQ----VRG-RG 187

  Fly   193 LPKDHEGLARVVRIEGIESNMCCGTHVTNLSQLQCIKLLYAEKVKANV--LVHFVVGERVLVKLG 255
            ||.||.|..|||.|||::|||||||||:|||.||.||:|..||.|.|.  |: |:.|.|||..:.
Mouse   188 LPDDHAGPIRVVTIEGVDSNMCCGTHVSNLSDLQVIKILGTEKGKKNKSNLI-FLAGNRVLKWME 251

  Fly   256 EVFQREQQLTQALKGGPGQHLELVQKLQQNVKGSRKYFQQLLKRYATAEAERLCDLPKKDRPKY- 319
            .....|:.||..||.|...|:|.|:|||...|..:|....||:..|...|..|     :..|.:
Mouse   252 RSHGSEKALTSLLKCGVEDHVEAVKKLQNATKLLQKNNLNLLRDLAVHTAHSL-----RSSPAWG 311

  Fly   320 --FSLHRRDGIEVDFINTFL-RAAPEGIFYFLTVSESVFAGSSAKGHLVLRGDPEIVGKLGPQFM 381
              .:|||::| :.:|:|... ....|....||||.:...||.     .:|.|..|.|..|||:..
Mouse   312 GVVTLHRKEG-DSEFMNIIANEIGSEETLLFLTVGDEKGAGL-----FLLAGPAEAVETLGPRVA 370

  Fly   382 EILEGKGNGKEDNFQGKINNLARLQECQELLE 413
            |:|||||.||:..||||...::|..|.|.||:
Mouse   371 EVLEGKGAGKKGRFQGKATKMSRRAEAQALLQ 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10802	NP_570062.1	AlaX	6..250	CDD:225427	125/248 (50%)
CG10802	NP_570062.1	tRNA_SAD	43..229	CDD:298782	99/188 (53%)
Aarsd1	NP_659078.1	AlaX	8..248	CDD:225427	126/248 (51%)
Aarsd1	NP_659078.1	tRNA_SAD	43..231	CDD:298782	103/195 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850360
Domainoid	1	1.000	166	1.000	Domainoid score	I3873
eggNOG	1	0.900	-	-		E1_COG2872
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6821
Inparanoid	1	1.050	289	1.000	Inparanoid score	I2796
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56694
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006113
OrthoInspector	1	1.000	-	-		oto93490
orthoMCL	1	0.900	-	-		OOG6_104566
Panther	1	1.100	-	-	LDO	PTHR43462
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2363
SonicParanoid	1	1.000	-	-		X5051
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790