DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10802 and aarsd1

DIOPT Version :9

Sequence 1:	NP_570062.1	Gene:	CG10802 / 31318	FlyBaseID:	FBgn0029664	Length:	436	Species:	Drosophila melanogaster
Sequence 2:	NP_001003572.1	Gene:	aarsd1 / 445178	ZFINID:	ZDB-GENE-040801-91	Length:	412	Species:	Danio rerio

Alignment Length:	432	Identity:	189/432 - (43%)
Similarity:	253/432 - (58%)	Gaps:	41/432 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVFKCQEDSFLKEFKTKIVSSEFATLDWTDPSGKVEKLKGFNVICEDTILFPEGGGQPCDYGTLG 65
            |.|:||.|.:::||.:.:||...|.|. .:.:|:.|||.||||..:||||||||||||.|:||:|
Zfish     1 MAFQCQRDCYMQEFDSCVVSCVPAELK-LENNGRKEKLTGFNVKLKDTILFPEGGGQPDDHGTIG 64

  Fly    66 GFPVKNVQRKGSTAVHFVESPTSFEQDAEVLLTLDYQRRLDHMQQHSGQHLITALFDREFKYDTT 130
            |.||..|.|:|..|||||.|  :.|:..||.:.||::||.|||||||||||||||.|..|.|.||
Zfish    65 GVPVLRVLRQGPDAVHFVSS--ALEEGQEVHIKLDWERRFDHMQQHSGQHLITALADTMFGYKTT 127

  Fly   131 SWSLGSTVSYIQLSTPHLISRESLDLIERQANDLIREGREVTVLLV---DPEVAQEFQDARAPRG 192
            ||.||...|.|:|.|. .:....::.:|...|:.||....|||.|:   ||.|    :..|: ||
Zfish   128 SWDLGRQRSSIELDTA-TVKPGEMEALETAVNEKIRAHVPVTVNLLSIDDPAV----EKVRS-RG 186

  Fly   193 LPKDHEGLARVVRIEGIESNMCCGTHVTNLSQLQCIKLLYAEKVKAN-VLVHFVVGERVLVKLGE 256
            ||.||.|..|::.|||:::||||||||:|||.||.||:|..||.|.| ..:.|:.|.|||....:
Zfish   187 LPDDHAGPIRIIDIEGVDANMCCGTHVSNLSHLQVIKILGTEKGKKNKTNLIFIAGNRVLKYAEK 251

  Fly   257 VFQREQQLTQALKGGPGQHLELVQKLQQNVKGSRKYFQQLLKRYATAEAERLCDLPKKDRPKYFS 321
            .:..|:.||..||.|..:|::.|.|||:.||..:|....:|:..|...|:.....|  ||..:||
Zfish   252 SYNIEKSLTVLLKTGADEHVDAVDKLQKTVKRLQKSNLTILREMAVLIAQNFKSKP--DRGHFFS 314

  Fly   322 LHRRDG---------IEVDFINTFLRAAPEGIFYFLTVSESVFAGSSAKGHLVLRGDPE-IVGKL 376
            ||.:||         .|:.|.:|.:         |:||.:...||      |.|...|| ||.::
Zfish   315 LHNKDGDNEFMNIVANEIGFQDTLI---------FMTVGDEKGAG------LFLIAGPENIVTEV 364

  Fly   377 GPQFMEILEGKGNGKEDNFQGKINNLARLQECQELL-EAEFK 417
            ||:..|:|:|||.||...:|||.|:|.:..|.:.|| |..:|
Zfish   365 GPRVSELLQGKGAGKAGRYQGKANSLVKRAEVEALLKERSYK 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10802	NP_570062.1	AlaX	6..250	CDD:225427	124/247 (50%)
CG10802	NP_570062.1	tRNA_SAD	43..229	CDD:298782	100/188 (53%)
aarsd1	NP_001003572.1	AlaX	8..248	CDD:225427	126/248 (51%)
aarsd1	NP_001003572.1	tRNA_SAD	42..230	CDD:298782	104/195 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596280
Domainoid	1	1.000	170	1.000	Domainoid score	I3746
eggNOG	1	0.900	-	-		E1_COG2872
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6821
Inparanoid	1	1.050	298	1.000	Inparanoid score	I2697
OMA	1	1.010	-	-		QHG56694
OrthoDB	1	1.010	-	-		D386458at33208
OrthoFinder	1	1.000	-	-		FOG0006113
OrthoInspector	1	1.000	-	-		oto38821
orthoMCL	1	0.900	-	-		OOG6_104566
Panther	1	1.100	-	-	LDO	PTHR43462
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5051
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.770