DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10802 and AlaRS

DIOPT Version :9

Sequence 1:	NP_570062.1	Gene:	CG10802 / 31318	FlyBaseID:	FBgn0029664	Length:	436	Species:	Drosophila melanogaster
Sequence 2:	NP_523511.2	Gene:	AlaRS / 34156	FlyBaseID:	FBgn0027094	Length:	966	Species:	Drosophila melanogaster

Alignment Length:	484	Identity:	98/484 - (20%)
Similarity:	170/484 - (35%)	Gaps:	122/484 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 FLKEFKTKIVSSEFATLDWTDPSGKVEKLKGFNVICEDTILFPEGGGQPCDYGTL-------GGF 67
            |..:|..:|.|.:.|                 .::.:.|..:.|.|||..|.|.|       ..|
  Fly   513 FENQFVNEITSGQKA-----------------GIVLDKTNFYAESGGQIYDQGALVKVNDEANEF 560

  Fly    68 PVKNVQRKGSTAVHFVESPTSFEQDAEVLLTLDYQRRLDHMQQHSGQHLITALFDREFKYDTTSW 132
            .|..|..:|...:|......:.:...|:.|.:|.:||...|:.||..|.:.....:....||.
  Fly   561 LVDRVYNRGGYILHIGVVEGTLKVGDELELHIDVERRWLTMKNHSATHALNHCLLQVLGKDTE-- 623

  Fly   133 SLGSTVSYIQL----STPHLISRESLDLIERQANDLIREGREVTVLLVDPEVAQEFQDARAPRGL 193
            ..||.|...:|    ::...::.|.:...|:...:::.  :.|.:...:.::|.    |:..|||
  Fly   624 QKGSLVVPEKLRFDFNSKAAMTIEQVSKTEQLTKEMVY--KNVPIYAKESKLAL----AKKIRGL 682

  Fly   194 --------PKDHEGLARVVRIEGIESN------------MCCGTHVTNLSQLQCIKLLYAEKVKA 238
                    |.....::..|.::.:|.|            .|.|||:.....:....:...|.:..
  Fly   683 RSVFDEVYPDPVRVISFGVPVDELEQNPDSEAGEQTSVEFCGGTHLRRSGHIMDFVISSEEAIAK 747

  Fly   239 NV-LVHFVVGERVL--VKLGEVFQREQQLTQAL----KGGPG--QHLELVQKLQQNV-------- 286
            .: .:..:.|...|  :|..|.|::|....:|.    |.|..  .|::.:.:|.:.:
  Fly   748 GIRRIVALTGPEALKALKKSEAFEQEIVRLKATIDNDKSGKDSKSHVKEIVELTEQISHATIPYV 812

  Fly   287 ---------KGSRKYFQQLLKRYATA-------EAERLCDLPKKDRPKYFSLHRRDGIEVDFINT 335
                     ||.:|......:....|       .|:.||:.    .|....|..:  :|. |.||
  Fly   813 KKDEMRNLLKGLKKTLDDKERALRAAVSVTVVERAKTLCEA----NPNATVLVEQ--LEA-FNNT 870

  Fly   336 -FLRAA--------PEGIFYFLTV---SESVFAGSSAKGHLVLRG------DPEIVGKLGPQFME 382
             .|.||        |:....||:|   |:.:|..||.....|.:|      ...:...||
  Fly   871 KALDAALKQVRSQLPDAAAMFLSVDADSKKIFCLSSVPKSAVEKGLKANEWVQHVSATLG----- 930

  Fly   383 ILEGKGNGKEDNFQGKINNLARLQECQEL 411
               |||.||.::.|....|..::.|..:|
  Fly   931 ---GKGGGKPESAQASGTNYEKVDEIVQL 956

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10802	NP_570062.1	AlaX	6..250	CDD:225427	51/271 (19%)
CG10802	NP_570062.1	tRNA_SAD	43..229	CDD:298782	44/216 (20%)
AlaRS	NP_523511.2	PLN02900	5..963	CDD:215487	98/484 (20%)
		AlaRS_core	6..253	CDD:238360
		tRNA_SAD	529..>626	CDD:298782	24/98 (24%)
		tRNA_SAD	694..752	CDD:285247	8/57 (14%)
		DHHA1	888..957	CDD:280440	20/77 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464491
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840