Protein Alignment CG10804 and Slc6a2

DIOPT Version :9

• Sequence 1: NP_001138150.1
• Gene: CG10804 / 31317
• FlyBaseID: FBgn0029663
• Length: 726
• Species: Drosophila melanogaster
• Sequence 2: NP_112633.2
• Gene: Slc6a2 / 83511
• RGDID: 621822
• Length: 617
• Species: Rattus norvegicus
• Alignment Length: 650
• Identity: 225/650 - (34%)
• Similarity: 333/650 - (51%)
• Gaps: 107/650 - (16%)

  Fly    93 AELVAIATASADQQDIVEGEKEGEERESWDSKIMFLLATIGYAVGLGNVWRFPYLAQKNGGGAFL 157
            |:|:.:...:..|..:...:.:.:.||:|..||.|||:.:|:||.|.||||||||..||||||||
  Rat    31 ADLLVVKEHNGVQCLLASQDGDAQPRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFL 95

  Fly   158 VPYFIMLCIQGIPIFYLELAIGQRLRKGAIGVWSQVSPYLGGIGISSAVVSYIVALYYNTIIAWC 222
            :||.:.|.|.|:|:||:|||:||..|:||..|| ::.|:..|:|.:..:::..|..|||.||||.
  Rat    96 IPYTLFLIIAGMPLFYMELALGQFNREGAATVW-KICPFFKGVGYAVILIALYVGFYYNVIIAWS 159

  Fly   223 LIYLLHSFESPLPWADC-----------PTRLYKNFTYDH-EPECVASSPTQFYWYRTTLQCSES 275
            |.||..||...|||.:|           |..|..:...|| :......:|...::.|..|...||
  Rat   160 LYYLFASFTLNLPWTNCGHAWNSPNCTDPKLLNASVLGDHTKYSKYKFTPAAEFYERGVLHLHES 224

  Fly   276 -----VDMPENFNYHMAIALIVSWFLVYICMVQGITSSGKIVYMTAIFPYVVLIIFFFRGITLKG 335
                 :.:|:   :.:.:.|:|...::|..:.:|:.:|||:|::||..||.||.:....|:||.|
  Rat   225 SGIHDIGLPQ---WQLLLCLMVVIVVLYFSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPG 286

  Fly   336 AADGVAHLFTPRWETLLDPVVWLEAGTQIFFSLGLAFGGLIAFSSYNPANNNCYRDAILVSLTNC 400
            |::|:.......:..|.:..||::|.||||||||..||.||||:|||..:|||||||:|.|..||
  Rat   287 ASNGINAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSTINC 351

  Fly   401 GTSMFAGVVVFSVIGFKATATFDRCTEERNGLVAQNKTHNLPVCDLQTELANSASGTGLAFIIFT 465
            .||..:|..:||::|:.|                  ..|.:.:.|:.||      |.||.|:::.
  Rat   352 VTSFISGFAIFSILGYMA------------------HEHKVKIEDVATE------GAGLVFVLYP 392

  Fly   466 EAINQFPGAQLWAVLFFLMLFTLGIDSQFGTLEGVVTSLVD--------MKLFPNLPKEYIVGAL 522
            |||:...|:..|||||||||..||:||..|.:|.|:|.|.|        .|||
  Rat   393 EAISTLSGSTFWAVLFFLMLLALGLDSSMGGMEAVITGLADDFQVLKRHRKLF------------ 445

  Fly   523 CFSCCTISM--------CFANGAGSYIFQLMDSFAGNFPLLIIALFECLSISYIYGVRRFSDDIE 579
               .|.:::        |...| |.|:..|:|:||....:|...|.|.:.:|:.|||.|||:||:
  Rat   446 ---TCAVTLGTFLLAMFCITKG-GIYVLTLLDTFAAGTSILFAVLMEAIGVSWFYGVDRFSNDIQ 506

  Fly   580 MMTGSRPNFYWMFCWKYLSPCAMVTILLAS---FYQLLTEGSSYPAWIGSKGATEGMEWPHWCIV 641
            .|.|.:|..||..|||::||..::.:::.|   |..|..:...||.|         ..|..|.|.
  Rat   507 QMMGFKPGLYWRLCWKFVSPAFLLFVVVVSIINFKPLTYDDYVYPPW---------ANWVGWGIA 562

  Fly   642 VAFFLILSSILWIPIVAVLRLCGIKVVEDSDPAWFPEAELREVHGIVPHEPTEL--ERSIFCFNM 704
                  |||::.:|...:.:...|:     ...|     .|..:||.|.....|  :|.:..|.:
  Rat   563 ------LSSMILVPAYVIYKFFSIR-----GSLW-----ERVAYGITPENEHHLVAQRDVRQFQL 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10804	NP_001138150.1	SLC6sbd-B0AT-like	120..661	CDD:271364	211/576 (37%)
Slc6a2	NP_112633.2	SLC5-6-like_sbd	56..615	CDD:382020	222/624 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810