Protein Alignment CG10804 and Slc6a21

DIOPT Version :10

• Sequence 1: NP_001138150.1
• Gene: CG10804 / 31317
• FlyBaseID: FBgn0029663
• Length: 726
• Species: Drosophila melanogaster
• Sequence 2: NP_001028348.2
• Gene: Slc6a21 / 76713
• MGIID: 1923963
• Length: 749
• Species: Mus musculus
• Alignment Length: 645
• Identity: 185/645 - (28%)
• Similarity: 310/645 - (48%)
• Gaps: 73/645 - (11%)

  Fly    65 MSDAFDESSELEQDPPPFGSEASTSKAKAELVAIATASADQQDIVEGEKEGEERES------WDS 123
            |..:|::..||:..|.   .|..|:..|::         :...:..|.:..|.|.:      ...
Mouse     1 MDQSFEDFLELKNKPV---EEVHTASKKSD---------NPTSVSRGFRTREVRVTKIPNHFQAK 53

  Fly   124 KIMFLLATIGYAVGLGNVWRFPYLAQKNGGGAFLVPYFIMLCIQGIPIFYLELAIGQRLRKGAIG 188
            |...:|..:.:::|||:.||||||..:||||:||:.|||:|.:.|||:.|:|:.|||.||...|.
Mouse    54 KTENILILVAFSIGLGSTWRFPYLCHQNGGGSFLLMYFILLLLLGIPLMYMEMVIGQWLRMDNIQ 118

  Fly   189 VWSQVSPYLGGIGISSAVVSYIVALYYNTIIAWCLIYLLHSFESPLPWADCPTRLYKNFTYDHEP 253
            .|..:.|:|.|:|.|:.:...:|.||.:.:::|.|.||..||:.||||.:||  |.:|.:.....
Mouse   119 AWKYLVPWLSGVGYSNILACVLVVLYNSALVSWSLFYLGQSFDYPLPWQNCP--LVENLSMVAGN 181

  Fly   254 ECVASSPTQFYWYRTTLQCSESVDMP-ENFNYHMAIALIVSWFLVYICMVQGITSSGKIVYMTAI 317
            .|:.|.|.|::||.|.||.|..::.. |....::.:.|..:|..:|:.||..|..|..::..:.:
Mouse   182 TCLWSEPHQYFWYHTLLQASNQMEEGIEVLVLNVTLCLFATWIFLYVTMVTRIKISVLMMIFSIL 246

  Fly   318 FPYVVLIIFFFRGITLKGAA-DGVAHLFTPRWETLLDPVVWLEAGTQIFFSLGLAFGGLIAFSSY 381
            |..|:|:.||.|.:.|.|:. ..:..|.|.....|.....|.:||..:.:||||..|.:|.||:|
Mouse   247 FSNVLLLCFFIRTLFLNGSVRASLWRLVTIELSILSSLDAWRQAGGHVLYSLGLGMGTIITFSTY 311

  Fly   382 NPANNNCYRDAILVSLTNCGTSMFAGVVVFSVIGFKATATFDRCTEER----------------- 429
            .|...|..:.|..|::.|..||:.:..|:|.|:||..|.:...|.:..
Mouse   312 QPRGENYIKWASFVAMVNLATSLLSSFVIFLVMGFWTTTSGTMCIKRSVSNLINLIANGVLPKAA 376

  Fly   430 ----------------------NGLVAQNKTHNLPVCDLQTELANSASGTGLAFIIFTEAINQFP 472
                                  |.|.:|.....|| |.:..:......|.||:::.|::||:.||
Mouse   377 WPPGDIIHKPPLEYLAWINQLPNNLKSQVIHQTLP-CSILIQKEKIMEGPGLSYVAFSQAISLFP 440

  Fly   473 GAQLWAVLFFLMLFTLGIDSQFGTLEGVV----TSLVDMKLFPNLPKEYIVGALCFSCCTISMCF 533
            |:..||::||:.|..:|:.:....|||:|    .|:......|||.:..:    |......|:.|
Mouse   441 GSSFWAIIFFMSLAIMGLGTMLTLLEGIVLPLQKSISTFAKHPNLVQVLV----CLGGFLGSLVF 501

  Fly   534 ANGAGSYIFQLMDSFAGNFPLLIIALFECLSISYIYGVRRFSDDIEMMTGSRPNFYWMFCWKYLS 598
            ::..|||:..|.|.......|:||.:.:.||::::||::||..::....||.....:.|.|.|::
Mouse   502 SSRPGSYVVFLFDDLLVPMVLIIIVVIQNLSLAWLYGIKRFRAEVFGQLGSLVWSPFTFLWSYVT 566

  Fly   599 PCAMVTILLASFYQLLTEGSS-YPAWIGSKGATEGMEWPHWCIVVAFFLILSSILWIPIV 657
            ...::.:|...|..|...||. |.:|  :...:..::.|:..|.:.:...||.:..:||:
Mouse   567 LPTLLVLLTIYFLNLYYSGSPYYVSW--NDSMSHEVKQPYKKIPLGWVTFLSVLALLPIL 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10804	NP_001138150.1	SLC6sbd-B0AT-like	120..661	CDD:271364	174/590 (29%)
Slc6a21	NP_001028348.2	SLC5-6-like_sbd	48..622	CDD:444915	172/582 (30%)