Protein Alignment CG10804 and SLC6A11

DIOPT Version :9

• Sequence 1: NP_001138150.1
• Gene: CG10804 / 31317
• FlyBaseID: FBgn0029663
• Length: 726
• Species: Drosophila melanogaster
• Sequence 2: NP_055044.1
• Gene: SLC6A11 / 6538
• HGNCID: 11044
• Length: 632
• Species: Homo sapiens
• Alignment Length: 626
• Identity: 234/626 - (37%)
• Similarity: 333/626 - (53%)
• Gaps: 74/626 - (11%)

  Fly    81 PFGS-----EASTSKAKAELVAIATASADQQDIVEGEKEGEERESWDSKIMFLLATIGYAVGLGN 140
            |.|:     ||..|:|.....:...|:..:...|:.:|...||..|::|:.|:|:..|..:||||
Human     8 PLGNGKAAEEARESEAPGGGCSSGGAAPARHPRVKRDKAVHERGHWNNKVEFVLSVAGEIIGLGN 72

  Fly   141 VWRFPYLAQKNGGGAFLVPYFIMLCIQGIPIFYLELAIGQRLRKGAIGVWSQVSPYLGGIGISSA 205
            |||||||..||||||||:||.:.....|||:|:||.|:||...:|.|..|.:|.|...|||.::.
Human    73 VWRFPYLCYKNGGGAFLIPYVVFFICCGIPVFFLETALGQFTSEGGITCWRKVCPLFEGIGYATQ 137

  Fly   206 VVSYIVALYYNTIIAWCLIYLLHSFESPLPWADC----PTRLYKNF------TYDHEPECVASSP 260
            |:...:.:||..|:||.:.||.:.|.:.||||.|    .|.....|      .|.|.....|:||
Human   138 VIEAHLNVYYIIILAWAIFYLSNCFTTELPWATCGHEWNTENCVEFQKLNVSNYSHVSLQNATSP 202

  Fly   261 TQFYWYRTTLQCSESVDMPENFNYHMAIALIVSWFLVYICMVQGITSSGKIVYMTAIFPYVVLII 325
            ...:|....|..|:.::...|..:.:|:.|:.:|.:.|.|:.:|..|:||:||:||.|||::|:|
Human   203 VMEFWEHRVLAISDGIEHIGNLRWELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLI 267

  Fly   326 FFFRGITLKGAADGVAHLFTPRWETLLDPVVWLEAGTQIFFSLGLAFGGLIAFSSYNPANNNCYR 390
            ...||:||.||::|:.....|....|.||.||::||||||||..:..|.|.|..|||..||||||
Human   268 LLIRGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTALGSYNNYNNNCYR 332

  Fly   391 DAILVSLTNCGTSMFAGVVVFSVIGFKATATFDRCTEERNGLVAQNKTHNLPVCDLQTELANSAS 455
            |.|::...|.|||..||..:|||:||.|                  ....:|:.::      :.|
Human   333 DCIMLCCLNSGTSFVAGFAIFSVLGFMA------------------YEQGVPIAEV------AES 373

  Fly   456 GTGLAFIIFTEAINQFPGAQLWAVLFFLMLFTLGIDSQFGTLEGVVTSLVDM--KLF-PNLPKEY 517
            |.|||||.:.:|:...|.:.|||.|||:||..||:||||..:|.:||::|||  |:| ....:|.
Human   374 GPGLAFIAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYRREL 438

  Fly   518 IVGALCFSCCTISMCFANGAGSYIFQLMDSFAGN-FPLLIIALFECLSISYIYGVRRFSDDIEMM 581
            ::.||......:.:......|.|||||.||:|.: ..||.:|:|||:.|.::||..||.|:||.|
Human   439 LILALSVISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECICIGWVYGSNRFYDNIEDM 503

  Fly   582 TGSRPNFYWMFCWKYLSP--CAMVTILLASFYQLLTEGS--SYPAWIGSKGATEGMEWPHWCIVV 642
            .|.||.....:||..::|  ||.:.|.....|:.|...:  :||||      ..|:.|
Human   504 IGYRPPSLIKWCWMIMTPGICAGIFIFFLIKYKPLKYNNIYTYPAW------GYGIGW------- 555

  Fly   643 AFFLILSSILWIPIVAVLRLCGIKVVEDSDPAWFPEAELRE 683
              .:.|||:|.||    |.:| |.|       |..|..|.|
Human   556 --LMALSSMLCIP----LWIC-ITV-------WKTEGTLPE 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10804	NP_001138150.1	SLC6sbd-B0AT-like	120..661	CDD:271364	215/558 (39%)
SLC6A11	NP_055044.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..41		7/32 (22%)
		SLC6sbd_GAT3	49..590	CDD:212077	225/585 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810