DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10804 and slc6a16b

DIOPT Version :9

Sequence 1:	NP_001138150.1	Gene:	CG10804 / 31317	FlyBaseID:	FBgn0029663	Length:	726	Species:	Drosophila melanogaster
Sequence 2:	NP_001103944.1	Gene:	slc6a16b / 567809	ZFINID:	ZDB-GENE-070424-95	Length:	676	Species:	Danio rerio

Alignment Length:	601	Identity:	246/601 - (40%)
Similarity:	354/601 - (58%)	Gaps:	59/601 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   105 QQDIVEGEKEGEE--------RESWDSKIMFLLATIGYAVGLGNVWRFPYLAQKNGGGAFLVPYF 161
            |||.|| .:.|.|        |:.||||:.:.||.:|::||||||||||||..:||||||::.|.
Zfish    13 QQDEVE-LRLGLEPEVPLETARDGWDSKVEYFLAQVGFSVGLGNVWRFPYLCHQNGGGAFILLYV 76

  Fly   162 IMLCIQGIPIFYLELAIGQRLRKGAIGVWSQVSPYLGGIGISSAVVSYIVALYYNTIIAWCLIYL 226
            :::.:.|:|:|:||||.||.:|:|:||||..:||.|.|||.||.||.:.||||||.||.|.:.||
Zfish    77 VLMALVGVPLFFLELAAGQSIRQGSIGVWRHISPKLVGIGYSSCVVCFFVALYYNVIIGWSIFYL 141

  Fly   227 LHSFESPLPWADCPTRLYKNFTYDHEPECVASSPTQFYWYRTTLQCSESVDMPENFNYHMAIALI 291
            .:||:.||||..|||.  .|.|.   .||.|||||.::|||..|..::|:|....||:.:...|:
Zfish   142 GNSFQYPLPWEKCPTE--GNSTV---KECAASSPTAYFWYRKALDITDSIDETGEFNFILTGCLL 201

  Fly   292 VSWFLVYICMVQGITSSGKIVYMTAIFPYVVLIIFFFRGITLKGAADGVAHLFTPRWETLLDPVV 356
            .:|.:|.:.|.:||.||||::|.:::||||||:.|..||:||.||::|:..:|.||.|...|..|
Zfish   202 AAWVIVCLAMYKGIKSSGKVMYFSSVFPYVVLLCFLIRGVTLDGASEGIKFMFYPRLEIWADVQV 266

  Fly   357 WLEAGTQIFFSLGLAFGGLIAFSSYNPANNNCYRDAILVSLTNCGTSMFAGVVVFSVIGFKATAT 421
            |.:|.||:||:|||.||.:||:|||||.||||:|||..||..|..||:.|.:|||:|:||:|...
Zfish   267 WRQAATQVFFALGLGFGSVIAYSSYNPRNNNCHRDAFTVSGVNFMTSVLATLVVFAVLGFRAKTI 331

  Fly   422 FDRCTEERN--------------------------------------GLVAQNKTHNLPVCDLQT 448
            ...|. :||                                      |:......:|:..|.|:.
Zfish   332 AAECV-KRNLKALLKVTSSAPLPVLSINASDVESISLDEYANWYSTQGMELSISDYNITACSLED 395

  Fly   449 ELANSASGTGLAFIIFTEAINQFPGAQLWAVLFFLMLFTLGIDSQFGTLEGVVTSLVDMKLFPNL 513
            ||......||||||.||||:..|||:..|:.||||||..||:.:.|||:.|::|.|.|  .|..|
Zfish   396 ELRQGVEETGLAFIAFTEAMTLFPGSPFWSALFFLMLLNLGLSTMFGTMAGILTPLTD--TFKTL 458

  Fly   514 PKEYIVGALCFSCC---TISMCFANGAGSYIFQLMDSFAGNFPLLIIALFECLSISYIYGVRRFS 575
            ....::..:| ||.   .|.:.|....|:|...:.|.::...||:|:.:|:.:|:|::||..||.
Zfish   459 RNHKLIFTIC-SCTVGFVIGLVFTQRCGNYFVTMFDDYSATLPLIIVVIFQTISVSWVYGADRFL 522

  Fly   576 DDIEMMTGSRPNFYWMFCWKYLSPCAMVTILLASFYQLLTEGSSYPAWIGSKGATEGMEWPHWCI 640
            :|::.|........:.:.||::.|.||:.:|.||..:::.:...|.||...|.:.|.:.:|.|.:
Zfish   523 EDLKQMLNRPVPVIYKYLWKFVCPIAMLGLLGASLLKMILKRPEYSAWNREKASKEDLPYPDWAL 587

  Fly   641 VVAFFLILSSILWIPI 656
            .|...||:.:.|.:||
Zfish   588 AVLIILIIIASLPVPI 603

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10804	NP_001138150.1	SLC6sbd-B0AT-like	120..661	CDD:271364	238/578 (41%)
slc6a16b	NP_001103944.1	SLC6sbd-B0AT-like	33..607	CDD:271364	239/580 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48419
OrthoDB	1	1.010	-	-		D251682at33208
OrthoFinder	1	1.000	-	-		FOG0001784
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101967
Panther	1	1.100	-	-	O	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.930