Protein Alignment CG10804 and slc6a8

DIOPT Version :9

• Sequence 1: NP_001138150.1
• Gene: CG10804 / 31317
• FlyBaseID: FBgn0029663
• Length: 726
• Species: Drosophila melanogaster
• Sequence 2: NP_001314797.1
• Gene: slc6a8 / 567544
• ZFINID: ZDB-GENE-071024-2
• Length: 652
• Species: Danio rerio
• Alignment Length: 711
• Identity: 246/711 - (34%)
• Similarity: 363/711 - (51%)
• Gaps: 128/711 - (18%)

  Fly    23 SIDQLELRELRGRLVSKEHGVSHHHHTSLHHQPLYGATNQGFMSDAFDESSELEQDPPPFGSEAS 87
            :::.:.:.|.:|.|:...:.          |..:.|..|.|.||                   |:
Zfish    12 ALNMVLVEEKKGHLIPNGNA----------HPSVNGTLNGGPMS-------------------AA 47

  Fly    88 TSKAKAELVAIATASADQQDIVEGEKEG-EERESWDSKIMFLLATIGYAVGLGNVWRFPYLAQKN 151
            |....|               ||.::|| .|||:|..::.|:::.:|:|||||||||||||..||
Zfish    48 TGAISA---------------VEKKREGYPERETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKN 97

  Fly   152 GGGAFLVPYFIMLCIQGIPIFYLELAIGQRLRKGAIGVWSQVSPYLGGIGISSAVVSYIVALYYN 216
            |||.||:||.:.:.:.|||||:||:|:||.::.|:|.||: ::|...|:|.:|.|:.:....||.
Zfish    98 GGGVFLIPYVLFIFLGGIPIFFLEIALGQFMKAGSINVWN-IAPLFKGLGYASMVIVFFCNTYYI 161

  Fly   217 TIIAWCLIYLLHSFESPLPWA------------------DCPTRLYKNFTYDH---EPECVASSP 260
            .::||...|.:.||.:.|||:                  ||......|.|:.:   |......||
Zfish   162 MVLAWGFYYFIKSFNATLPWSTCDNPWNTENCIEIFRQGDCKNGTIGNSTFGNLTCEELANGRSP 226

  Fly   261 TQFYWYRTTLQCSESVDMPENFNYHMAIALIVSWFLVYICMVQGITSSGKIVYMTAIFPYVVLII 325
            ...:|....|..|:.:|.|...|:.:.:.|:..|.:||.|:.:|:.|:|||||.||.||||||||
Zfish   227 IIEFWENKVLNISDGLDEPGAVNWELMLCLLAVWVMVYFCVWKGVKSTGKIVYFTATFPYVVLII 291

  Fly   326 FFFRGITLKGAADGVAHLFTPRWETLLDPVVWLEAGTQIFFSLGLAFGGLIAFSSYNPANNNCYR 390
            ...||:||.||.||:.:...|.|..|.:..||::||||||||..:..|.|.|..|||..||:||:
Zfish   292 LLVRGVTLPGAYDGILYYVKPDWSKLGEAQVWIDAGTQIFFSYAIGLGALTALGSYNRFNNDCYK 356

  Fly   391 DAILVSLTNCGTSMFAGVVVFSVIGFKATATFDRCTEERNGLVAQNKTHNLPVCDLQTELANSA- 454
            ||.:::|.|.|||.|||.||||::||.|:                         :...:::..|
Zfish   357 DAFVLALINSGTSFFAGFVVFSILGFMAS-------------------------EQGVDISKVAE 396

  Fly   455 SGTGLAFIIFTEAINQFPGAQLWAVLFFLMLFTLGIDSQFGTLEGVVTSLVDM---KLFPNLPKE 516
            ||.|||||.:.:|::..|.|.:||.|||:||..||:||||..:||.||.::|:   |.:....:|
Zfish   397 SGPGLAFIAYPKAVSMMPVAPVWAALFFIMLLLLGLDSQFVGVEGFVTGILDLFPGKYYMRYQRE 461

  Fly   517 YIVGALCFSCCTISMCFANGAGSYIFQLMDSF-AGNFPLLIIALFECLSISYIYGVRRFSDDIEM 580
            ..|...|..|..|.:......|.|:|||.|.: |....||..|.:||:.::::||..||.|||..
Zfish   462 IAVAICCLLCFIIDLSMVTQGGMYVFQLFDYYSASGMTLLWQAFWECVVVAWVYGADRFMDDIAR 526

  Fly   581 MTGSRPNFYWM-FCWKYLSPCAMVTILLASF--YQLLTEGSSYPAWIGSKGATEGMEWPHWCIVV 642
            |.|.|| |.|| :||..::||..:.|.|...  |:.||..:.|             .:|.|..|:
Zfish   527 MIGYRP-FPWMKWCWSIITPCVCMGIFLFHLLNYKPLTYNNVY-------------VYPWWGEVI 577

  Fly   643 AFFLILSSILWIPIVAVLRLCGIKVV-----ED-SDPAW--------FPEAELREVHGIVP 689
            .:.|.|||:|.||:..|.:|.|.|..     |: :.|.|        .|:.:::.:..:.|
Zfish   578 GWCLALSSMLCIPVSLVYKLSGAKGTFKERWENLTKPVWGAHHLEYMAPDTDIKSLASLSP 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10804	NP_001138150.1	SLC6sbd-B0AT-like	120..661	CDD:271364	219/569 (38%)
slc6a8	NP_001314797.1	SLC6sbd_CT1	64..652	CDD:271397	229/615 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810