Protein Alignment CG10804 and SLC6A20

DIOPT Version :10

• Sequence 1: NP_001138150.1
• Gene: CG10804 / 31317
• FlyBaseID: FBgn0029663
• Length: 726
• Species: Drosophila melanogaster
• Sequence 2: NP_001372612.1
• Gene: SLC6A20 / 54716
• HGNCID: 30927
• Length: 603
• Species: Homo sapiens
• Alignment Length: 607
• Identity: 260/607 - (42%)
• Similarity: 361/607 - (59%)
• Gaps: 61/607 - (10%)

  Fly   118 RESWDSKIMFLLATIGYAVGLGNVWRFPYLAQKNGGGAFLVPYFIMLCIQGIPIFYLELAIGQRL 182
            |..|.:.:.|:.|.|.||||||||||||||.|..|||:|||||.|||.::|:|:.|||||:|||:
Human     5 RPLWANSLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLYLELAVGQRM 69

  Fly   183 RKGAIGVWSQVSPYLGGIGISSAVVSYIVALYYNTIIAWCLIYLLHSFESPLPWADCPTRLYKNF 247
            |:|:||.|..:||||.|:|::|.|||:.:::|||.|.||...||.|||:.||||:.||  |..|.
Human    70 RQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWAFWYLFHSFQDPLPWSVCP--LNGNH 132

  Fly   248 T-YDHEPECVASSPTQFYWYRTTLQCSESVDMPENFNYHMAIALIVSWFLVYICMVQGITSSGKI 311
            | ||.  ||..:|.||::|||.||..|.|:.......:..|:.|:::|.:||:|:::|..|:||:
Human   133 TGYDE--ECEKASSTQYFWYRKTLNISPSLQENGGVQWEPALCLLLAWLVVYLCILRGTESTGKV 195

  Fly   312 VYMTAIFPYVVLIIFFFRGITLKGAADGVAHLFTPRW-----------ETLLDPVVWLEAGTQIF 365
            ||.||..||.||||:..||:||.||.:|:.::|||:.           |.|.:|..|:.|.||||
Human   196 VYFTASLPYCVLIIYLIRGLTLHGATNGLMYMFTPKGSSALSLLAFQIEQLANPKAWINAATQIF 260

  Fly   366 FSLGLAFGGLIAFSSYNPANNNCYRDAILVSLTNCGTSMFAGVVVFSVIGFKATATFDRCTE--- 427
            |||||.||.||||:|||..:|||.:.||:|||.|..||:||.:|.||:.|||||..::.|.:
Human   261 FSLGLGFGSLIAFASYNEPSNNCQKHAIIVSLINSFTSIFASIVTFSIYGFKATFNYENCLKKVS 325

  Fly   428 ---------ERNGLVAQNKTH------------------NLPVCDLQTELANSASGTGLAFIIFT 465
                     |...|.|.|...                  .:..|.|::||..:..|||||||::|
Human   326 LLLTNTFDLEDGFLTASNLEQVKGYLASAYPSKYSEMFPQIKNCSLESELDTAVQGTGLAFIVYT 390

  Fly   466 EAINQFPGAQLWAVLFFLMLFTLGIDSQFGTLEGVVTSLVDMKLF-PNLPKEYIVGALCFSCCTI 529
            |||.....:|||:||:|.||..|||.|..|....::|.|.|.|:. .:||||.|.|.:|...|.|
Human   391 EAIKNMEVSQLWSVLYFFMLLMLGIGSMLGNTAAILTPLTDSKIISSHLPKEAISGLVCLVNCAI 455

  Fly   530 SMCFANGAGSYIFQLMDSFAGNFPLLIIALFECLSISYIYGVRRFSDDIEMMTGSRPNFYWMFCW 594
            .|.|...||:|.|.:.:.:|....||:|.|.|.:::.|:||:|||..|::.|||...::||...|
Human   456 GMVFTMEAGNYWFDIFNDYAATLSLLLIVLVETIAVCYVYGLRRFESDLKAMTGRAVSWYWKVMW 520

  Fly   595 KYLSPCAMVTILLASFY---QLLTEGSSYPAWIGSKGATEGMEWPHWCIVVAFFLILSSILWIPI 656
            ..:||..:|::.:  ||   .:||....|.||..|:|.....::|.:.:.|...|:.||.:.||:
Human   521 AGVSPLLIVSLFV--FYLSDYILTGTLKYQAWDASQGQLVTKDYPAYALAVIGLLVASSTMCIPL 583

  Fly   657 VAVLRLCGIKVVE-----DSDP 673
            .|:    |..|..     |:||
Human   584 AAL----GTFVQRRLKRGDADP 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10804	NP_001138150.1	SLC6sbd-B0AT-like	120..661	CDD:271364	254/586 (43%)
SLC6A20	NP_001372612.1	SLC6sbd_SIT1	2..588	CDD:271401	255/592 (43%)