Protein Alignment CG10804 and Slc6a12

DIOPT Version :9

• Sequence 1: NP_001138150.1
• Gene: CG10804 / 31317
• FlyBaseID: FBgn0029663
• Length: 726
• Species: Drosophila melanogaster
• Sequence 2: NP_059031.1
• Gene: Slc6a12 / 50676
• RGDID: 620255
• Length: 628
• Species: Rattus norvegicus
• Alignment Length: 632
• Identity: 219/632 - (34%)
• Similarity: 325/632 - (51%)
• Gaps: 90/632 - (14%)

  Fly    58 GATNQGFMSDAFDESSELEQDPPPFGSEASTSKAKAELVAIATASADQQDIVEGEKEGEERESWD 122
            ||..:.....:.|....:.:|..|.   .|....:.|::       ||:|    :.:.::|..|.
  Rat     4 GAWEERVSLSSMDRKVTVHEDGCPV---VSWVPEEGEMM-------DQKD----KDQVKDRGQWT 54

  Fly   123 SKIMFLLATIGYAVGLGNVWRFPYLAQKNGGGAFLVPYFIMLCIQGIPIFYLELAIGQRLRKGAI 187
            :|:.|:|:..|..:|||||||||||..|||||||.:||||.....|||:|:||:|:||...:|::
  Rat    55 NKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFFSCGIPVFFLEVALGQYSSQGSV 119

  Fly   188 GVWSQVSPYLGGIGISSAVVSYIVALYYNTIIAWCLIYLLHSFESPLPWADCPTRLYKNFTYDHE 252
            ..|.::.|.|.|||::|.|:...:.:||..|:||.|.||..||...|||..|.    .::..:|
  Rat   120 TAWRKICPLLQGIGMASVVIESYLNIYYIIILAWALFYLFSSFTWELPWTTCT----NSWNTEH- 179

  Fly   253 PECV----------------ASSPTQFYWYRTTLQCSESVDMPENFNYHMAIALIVSWFLVYICM 301
              ||                .:||...:|.|..|..:..:....:..:.:|:.|:::|.:.|.|:
  Rat   180 --CVDFLNYSSTRAASYSENFTSPVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWIICYFCI 242

  Fly   302 VQGITSSGKIVYMTAIFPYVVLIIFFFRGITLKGAADGVAHLFTPRWETLLDPVVWLEAGTQIFF 366
            .:|:.|:||:||.||.|||::|||...||:||.||..|:.....|....|.||.||::|||||||
  Rat   243 WKGVKSTGKVVYFTATFPYLMLIILLIRGVTLPGAYQGIVFYLKPDLLRLKDPQVWMDAGTQIFF 307

  Fly   367 SLGLAFGGLIAFSSYNPANNNCYRDAILVSLTNCGTSMFAGVVVFSVIGFKATATFDRCTEERNG 431
            |..:..|.|.|..|||..:||||||:|.:...|..||..||.||||::||.|
  Rat   308 SFAICQGCLTALGSYNKYHNNCYRDSIALCFLNSATSFVAGFVVFSILGFMA------------- 359

  Fly   432 LVAQNKTHNLPVCDLQTELANSASGTGLAFIIFTEAINQFPGAQLWAVLFFLMLFTLGIDSQFGT 496
                 :...:|:.::      :.||.|||||.|.:|:...|.:|||:.||||||..||:||||..
  Rat   360 -----QEQGVPISEV------AESGPGLAFIAFPKAVTMMPLSQLWSCLFFLMLLFLGLDSQFVC 413

  Fly   497 LEGVVTSLVDMKLFPNL-----PKEYIVGALCFSCCTISMCFANGAGSYIFQLMDSFAGN-FPLL 555
            :|.:||:.:||  ||..     .:|.::.|:...|..:.:......|.|||||.|.:|.: ..||
  Rat   414 MECLVTASMDM--FPQQLRKRGRRELLILAVAIVCYLMGLLLVTEGGMYIFQLFDYYASSGICLL 476

  Fly   556 IIALFECLSISYIYGVRRFSDDIEMMTGSRPNFYW---MFCWKYLSP--CAMVTILLASFYQLLT 615
            .::|||.:.|.::||..||.|::|.|.|.||   |   ...|.:|:|  |........|.|..|.
  Rat   477 FLSLFEVICIGWVYGADRFYDNVEDMIGYRP---WPLVKISWLFLTPGLCLATFFFSLSKYTPLK 538

  Fly   616 EGSSYPAWIGSKGATEGMEWPHWCIVVAFFLILSSILWIPIVAVLRL 662
            ..:.|             .:|.|...:.:.|..||:..:|:..::.|
  Rat   539 YNNVY-------------IYPSWGYSIGWLLAFSSMACVPLFIIITL 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10804	NP_001138150.1	SLC6sbd-B0AT-like	120..661	CDD:271364	207/567 (37%)
Slc6a12	NP_059031.1	SLC5-6-like_sbd	49..589	CDD:294310	209/573 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900