Protein Alignment CG10804 and Slc6a21

DIOPT Version :10

• Sequence 1: NP_001138150.1
• Gene: CG10804 / 31317
• FlyBaseID: FBgn0029663
• Length: 726
• Species: Drosophila melanogaster
• Sequence 2: NP_001102616.1
• Gene: Slc6a21 / 499151
• RGDID: 1562492
• Length: 743
• Species: Rattus norvegicus
• Alignment Length: 643
• Identity: 192/643 - (29%)
• Similarity: 312/643 - (48%)
• Gaps: 72/643 - (11%)

  Fly    65 MSDAFDESSELEQDPPPFGSEASTSKAKAELVAIATASADQQDIVEGEKEGEERESWDS------ 123
            |..:|:|..|.:::.|.  .|..|:..|         |.|...:..|.|..|.|.:..|
  Rat     1 MDQSFEEVPEPKKEEPT--EEEPTASKK---------STDPTSLSWGFKTREVRITKISSHFQAK 54

  Fly   124 KIMFLLATIGYAVGLGNVWRFPYLAQKNGGGAFLVPYFIMLCIQGIPIFYLELAIGQRLRKGAIG 188
            |...:|..:.:::|||:.||||||..:||||:||:.|.|:|.:.|||:.|:|:.|||.||...|.
  Rat    55 KTENILILVAFSIGLGSTWRFPYLCHQNGGGSFLLMYLILLLLLGIPLMYMEMVIGQWLRVDNIR 119

  Fly   189 VWSQVSPYLGGIGISSAVVSYIVALYYNTIIAWCLIYLLHSFESPLPWADCPTRLYKNFTYDHEP 253
            .|..:.|:|.|:|.||.:...:|.||.:.:::|.|.||..||:.|.||.:||  |.|||: ..:.
  Rat   120 AWKHLVPWLSGVGYSSMLACALVILYNSALVSWSLFYLGQSFDYPTPWENCP--LVKNFS-TSDI 181

  Fly   254 ECVASSPTQFYWYRTTLQCSESVDMP-ENFNYHMAIALIVSWFLVYICMVQGITSSGKIVYMTAI 317
            .|:.:.|.||:||.|.|:.|:.::.. |....::.:.|..:||.:||.||..|..|..::..:.:
  Rat   182 SCLRTEPHQFFWYHTVLRASDQIEEGIEVLVLNVTLCLFATWFFLYITMVTRIKISVLMMIFSIL 246

  Fly   318 FPYVVLIIFFFRGITLKGAADGVAHLFTPRWETLLDPVVWLEAGTQIFFSLGLAFGGLIAFSSYN 382
            ||.|:|..||.....:||..|.:..|.|.....|.....|.:||..:.:||||..|.:|.||||.
  Rat   247 FPNVLLFCFFTHIFFVKGVRDSLKRLVTTELSILASLDAWRQAGGHVLYSLGLGMGTIITFSSYQ 311

  Fly   383 PANNNCYRDAILVSLTNCGTSMFAGVVVFSVIGFKATATFDRCTEER---------NGLVAQ--- 435
            ....|..:.|..|::.|..||:.:..|:|.::||....:...|.|..         ||::.|
  Rat   312 TRGENYIKWASFVAMVNLMTSLLSSSVIFLMLGFWIENSGTPCVESNVSNLLSLIANGVLPQVAW 376

  Fly   436 ---NKTHNLPV-----------------------CDLQTELANSASGTGLAFIIFTEAINQFPGA 474
               :..|..|:                       |.:..:......|.|||::.|::||..|||:
  Rat   377 PPKDIIHRSPLEYLDWISQLPKNIRNEVAHFTLPCSILVQKEKFMEGPGLAYVAFSQAITLFPGS 441

  Fly   475 QLWAVLFFLMLFTLGIDSQFGTLEGVVTSLVDMKLFPNLPK--EYIVGALCFSCCTISMCFANGA 537
            ..||::||:.|..:|:.:....:||:..||  .|....|.|  :.:...:|......|:.|::..
  Rat   442 SFWAIIFFMSLVIMGLGTMTTLVEGIALSL--QKSISTLEKHPKLVPVIICLGGFLGSLVFSSRP 504

  Fly   538 GSYIFQLMDSFAGNFPLLIIALFECLSISYIYGVRRFSDDIEMMTGSRPNFYW---MFCWKYLSP 599
            |||:..|.|.......|::|..|:.||::::||::||..:   |.|......|   .|.|.|::.
  Rat   505 GSYVVFLFDDHLVPMVLIMIVAFQNLSLAWVYGIKRFRAE---MFGQLGRLVWAPFTFLWSYVTL 566

  Fly   600 CAMVTILLASFYQL-LTEGSSYPAWIGSKGATEGMEWPHWCIVVAFFLILSSILWIPI 656
            ..::.:|...|..| .:|..||.:|  :...::.::.|:..|.:.:...||.:..:||
  Rat   567 PTLLVLLTIYFLNLYFSESLSYVSW--NNSMSQEVKQPYQRIALGWVTFLSVLALLPI 622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10804	NP_001138150.1	SLC6sbd-B0AT-like	120..661	CDD:271364	178/588 (30%)
Slc6a21	NP_001102616.1	SLC5-6-like_sbd	50..621	CDD:444915	175/580 (30%)