Protein Alignment CG10804 and slc6a5

DIOPT Version :9

• Sequence 1: NP_001138150.1
• Gene: CG10804 / 31317
• FlyBaseID: FBgn0029663
• Length: 726
• Species: Drosophila melanogaster
• Sequence 2: NP_001009557.1
• Gene: slc6a5 / 494450
• ZFINID: ZDB-GENE-050105-2
• Length: 786
• Species: Danio rerio
• Alignment Length: 698
• Identity: 253/698 - (36%)
• Similarity: 373/698 - (53%)
• Gaps: 127/698 - (18%)

  Fly    58 GATNQGFMS-------------DAFDESSELEQDPPPFGSEASTSKAKAELVAIATASA------ 103
            |.....|||             ::..:.:.:.|.....|::.:||.....:....|...
Zfish   100 GKATSDFMSNNQSAVRIAAEHNNSTGDWTSMSQTTIILGTDGNTSVLPGTVTGPPTDDTGRLFQD 164

  Fly   104 DQQDIVEGEKEGEERESWDSKIMFLLATIGYAVGLGNVWRFPYLAQKNGGGAFLVPYFIMLCIQG 168
            |..|  :|..|.:.|.:|.:|:.|:|:.:||||||||||||||||.:|||||||:||.|||.:.|
Zfish   165 DDDD--DGGDENKARGNWSNKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLIMLGLAG 227

  Fly   169 IPIFYLELAIGQRLRKGAIGVWSQVSPYLGGIGISSAVVSYIVALYYNTIIAWCLIYLLHSFESP 233
            ||||.||:::||...:|.:.||..: |.|.|.||:..::|.::|:|||.|:.|.|.||..|.:..
Zfish   228 IPIFLLEVSLGQFASQGPVSVWKAI-PALQGCGIAMLIISVLIAIYYNIIMCWTLYYLFASLKET 291

  Fly   234 LPWADCPTR-------------------------LYKNFTYDHEPECVAS--------------- 258
            ||||.|...                         ..||.|:     |:::
Zfish   292 LPWATCKNEWNTVECKDKDMLLLDTCILRDRNITSIKNTTF-----CLSANVVGNLSKLLNVTVD 351

  Fly   259 -----SPTQFYWYRTTLQCSESVDMPENFNYHMAIALIVSWFLVYICMVQGITSSGKIVYMTAIF 318
                 ||::.|:....|..|:.::.|.:..:.:|..|.::|.:||..:.:||.||||:||.||.|
Zfish   352 NKTYVSPSEEYFKYNVLHISKGIEYPGDIRWPLAACLFLAWLIVYASLAKGIKSSGKVVYFTATF 416

  Fly   319 PYVVLIIFFFRGITLKGAADGVAHLFTPRWETLLDPVVWLEAGTQIFFSLGLAFGGLIAFSSYNP 383
            |||||:|...||:||.||..|:.:..||:||.|.|..||.:|.|||||||..|:||||..||||.
Zfish   417 PYVVLVILLIRGVTLPGAGSGILYFITPKWEKLNDAKVWKDAATQIFFSLSAAWGGLITLSSYNK 481

  Fly   384 ANNNCYRDAILVSLTNCGTSMFAGVVVFSVIGFKATATFDRCTEERNGLVAQNKTHNL--PVCDL 446
            .:||||||.::|:.||..||:|||.|:||||||.|                    |.|  |:..:
Zfish   482 FHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMA--------------------HELKVPIESV 526

  Fly   447 QTELANSASGTGLAFIIFTEAINQFPGAQLWAVLFFLMLFTLGIDSQFGTLEGVVTSLVDMKLFP 511
            ..|      |.|:||:::.||:.:.|.:..||::|||||.|||:|:.|.|:|.:|||:.|.  ||
Zfish   527 ADE------GPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSVSDE--FP 583

  Fly   512 NLPKEY---IVGALCFSCCTISMCFANGAGSYIFQLMDSFAGNFPLLIIALFECLSISYIYGVRR 573
            ...:::   .....|.|...:.......:|.|:.||:|:||.::.|:|||:||.:.||||||::|
Zfish   584 KYLRKHKPQFTLVCCLSFFVLGFPMITESGMYMLQLVDTFAASYSLVIIAIFELVGISYIYGLQR 648

  Fly   574 FSDDIEMMTGSRPNFYWMFCWKYLSPCAMVTILLASFYQLLTEGSSYPAWIGSKGAT-EGMEWPH 637
            |.:|||||.|.:||.:|..||.:::|..:..||..|.||          |   |..| |...:|:
Zfish   649 FCEDIEMMIGFQPNKFWRVCWAFVTPTILTFILALSLYQ----------W---KVMTYEDYTYPN 700

  Fly   638 WCIVVAFFLILSSILWIPIVAVLRLC--------GIKVVEDSDPAWFP 677
            |.:|:.:.:::.|::||||:..:::.        .:|:|....|.|.|
Zfish   701 WSMVLGWLMVICSVIWIPIMFAIKMHLAPGSLIERLKLVCSPQPDWGP 748

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10804	NP_001138150.1	SLC6sbd-B0AT-like	120..661	CDD:271364	234/591 (40%)
slc6a5	NP_001009557.1	SLC5-6-like_sbd	177..775	CDD:294310	240/619 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810