Protein Alignment CG10804 and slc6a1b

DIOPT Version :10

• Sequence 1: NP_001138150.1
• Gene: CG10804 / 31317
• FlyBaseID: FBgn0029663
• Length: 726
• Species: Drosophila melanogaster
• Sequence 2: NP_001007363.1
• Gene: slc6a1b / 492490
• ZFINID: ZDB-GENE-041114-57
• Length: 600
• Species: Danio rerio
• Alignment Length: 588
• Identity: 232/588 - (39%)
• Similarity: 333/588 - (56%)
• Gaps: 59/588 - (10%)

  Fly    83 GSEASTSKAKAELVAIATASADQQDI---VEGEKEGEERESWDSKIMFLLATIGYAVGLGNVWRF 144
            |::||......|:....||:...:.:   |:.:||..:||:|..|..|||:.:|||:||||||||
Zfish     5 GTKASDGHVLTEVNEAPTANDKPKTLVVKVQKKKELPDRETWQGKFDFLLSCVGYAIGLGNVWRF 69

  Fly   145 PYLAQKNGGGAFLVPYFIMLCIQGIPIFYLELAIGQRLRKGAIGVWSQVSPYLGGIGISSAVVSY 209
            |||..||||||||:|||:.|...|:|:|:||.|:||....|.:||| :::|...|:|:::||:|:
Zfish    70 PYLCGKNGGGAFLIPYFLTLIFAGVPLFFLETALGQYTSIGGLGVW-KLAPMFKGVGLAAAVLSF 133

  Fly   210 IVALYYNTIIAWCLIYLLHSFESPLPWADCPT-----RLYKNFTYDHEPECVASSPTQFYWYRTT 269
            .:.:||..||||.:.||.:||.:.|||..|..     :.:.|::..:... :.|:..:| |.|..
Zfish   134 WLNIYYIVIIAWAIYYLYNSFTTDLPWKSCDNPWNTDKCFSNYSMANIGN-MTSAVVEF-WERNM 196

  Fly   270 LQCSESVDMPENFNYHMAIALIVSWFLVYICMVQGITSSGKIVYMTAIFPYVVLIIFFFRGITLK 334
            .|.::.::.|......:||.|.::|.|||.|:.:|:..:||:||.:|.:||.:|.|.|.||:||.
Zfish   197 HQLTDGLEKPGEIRLPLAITLAIAWVLVYFCIWKGVGWTGKVVYFSATYPYFMLFILFIRGVTLP 261

  Fly   335 GAADGVAHLFTPRWETLLDPVVWLEAGTQIFFSLGLAFGGLIAFSSYNPANNNCYRDAILVSLTN 399
            ||.:|:....||.:..|.:..|||:|.||||||.||..|.|||..||||.|||.|:|:|:|...|
Zfish   262 GAKEGILFYVTPEFSKLKESEVWLDAATQIFFSYGLGLGSLIALGSYNPFNNNVYKDSIIVCCIN 326

  Fly   400 CGTSMFAGVVVFSVIGFKATATFDRCTEERNGLVAQNKTHNLPVCDLQTELANSASGTGLAFIIF 464
            ..||||||.|:||::||.|..|                  ..|:.|:      :|||.||||:.:
Zfish   327 SFTSMFAGFVIFSIVGFMAHIT------------------KRPIADV------AASGPGLAFLAY 367

  Fly   465 TEAINQFPGAQLWAVLFFLMLFTLGIDSQFGTLEGVVTSLVDMKLFPNL---PKEYIVGALCFSC 526
            .||:.|.|.:.|||||||.||..|||||||.|:||.:|:|||.  ||..   .:|..:..:|...
Zfish   368 PEAVTQLPISPLWAVLFFSMLLMLGIDSQFCTVEGFITALVDE--FPRALRGRREIFIAVVCLVS 430

  Fly   527 CTISMCFANGAGSYIFQLMDSF-AGNFPLLIIALFECLSISYIYGVRRFSDDIEMMTGSRPNFYW 590
            ..|.:......|.|:|:|.|.: |....||.:..|||:|||:.|||.:|..::|.|.|.:|..:|
Zfish   431 YLIGLSNITQGGLYVFKLFDYYSASGMCLLFLVFFECVSISWFYGVNKFYGNLEEMIGYKPCIWW 495

  Fly   591 MFCWKYLSPCAMVTILLASFYQ---LLTEGSSYPAWIGSKGATEGMEWPHWCIVVAFFLILSSIL 652
            ..||...:|..:..:.|.|..|   |......:|.|....|         ||      :.|||::
Zfish   496 KLCWVVFTPLIVAGVFLFSAVQMVPLTLNNYVFPKWGQGVG---------WC------MALSSMV 545

  Fly   653 WIP 655
            .||
Zfish   546 LIP 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10804	NP_001138150.1	SLC6sbd-B0AT-like	120..661	CDD:271364	221/548 (40%)
slc6a1b	NP_001007363.1	SLC5-6-like_sbd	2..600	CDD:444915	232/588 (39%)