Protein Alignment CG10804 and SLC6A16

DIOPT Version :10

• Sequence 1: NP_001138150.1
• Gene: CG10804 / 31317
• FlyBaseID: FBgn0029663
• Length: 726
• Species: Drosophila melanogaster
• Sequence 2: XP_047294657.1
• Gene: SLC6A16 / 28968
• HGNCID: 13622
• Length: 795
• Species: Homo sapiens
• Alignment Length: 700
• Identity: 197/700 - (28%)
• Similarity: 346/700 - (49%)
• Gaps: 79/700 - (11%)

  Fly    66 SDAFDESSELEQDPPPFGSEASTSKAK-AE-------------LVAIATASADQQDIVEGEKEGE 116
            |..:::...|.:....:.|||..|.|: ||             |.|:..::.:|:...|..:..|
Human    88 SQTWEDKGSLTRSATSWTSEAQVSAARVAEAQARTSQPKQISVLEALTASALNQKPTHEKVQMTE 152

  Fly   117 ERES--------WDSKIMFLLATIGYAVGLGNVWRFPYLAQKNGGGAFLVPYFIMLCIQGIPIFY 173
            ::||        |.||..::||.:|:::....:|||.||...:||.:|...|..||.:.|:|:.:
Human   153 KKESEVLLARPFWSSKTEYILAQVGFSMKPSCLWRFAYLWLNSGGCSFAAIYIFMLFLVGVPLLF 217

  Fly   174 LELAIGQRLRKGAIGVWSQVSPYLGGIGISSAVVSYIVALYYNTIIAWCLIYLLHSFESPLPWAD 238
            ||:|.||.:|:|.:|||..::|::||:|.||.:|.:|:.||:|.:.:|.:.|:..||:.|:||..
Human   218 LEMAAGQSMRQGGMGVWKIIAPWIGGVGYSSFMVCFILGLYFNVVNSWIIFYMSQSFQFPVPWEK 282

  Fly   239 CPTRLYKNFTYDHEPECVASSPTQFYWYRTTLQCSESVDMPENFNYHMAIALIVSWFLVYICMVQ 303
            ||..:..:   ..:|||..::|:.::||:..|:.|:.::...:..|.:.:...:.|.||...|:.
Human   283 CPLTMNSS---GFDPECERTTPSIYFWYQQALKASDRIEDGGSPVYSLVLPFFLCWCLVGAFMIN 344

  Fly   304 GITSSGKIVYMTAIFPYVVLIIFFFRGITLKGAADGVAHLFTPRWETLLDPVVWLEAGTQIFFSL 368
            |:.|:||::|:..:.|..:::.||.|.:.|:||..|:..|...:...:.:..||..||.|:..:.
Human   345 GLKSTGKVIYVLVLLPCFIIVGFFIRTLLLEGAKFGLQQLVVAKISDVYNMSVWSLAGGQVLSNT 409

  Fly   369 GLAFGGLIAFSSYNPANNNCYRDAILVSLTNCGTSMFAGVVVFSVIGFKATATFDRCTEERNGLV 433
            |:..|.:.:.:||.|.:|||..||.|||:.|..|.:......|.|:||.||....||.|....::
Human   410 GIGLGSVASLASYMPQSNNCLSDAFLVSVINLLTLLVFTSFNFCVLGFWATVITHRCCERNAEIL 474

  Fly   434 AQ---------------NKTHN-----------LP------------VCDLQTELANSASGTGLA 460
            .:               |..:|           ||            .|:::|:...::.|...|
Human   475 LKLINLGKLPPDAKPPVNLLYNPTSIYNAWLSGLPQHIKSMVLREVTECNIETQFLKASEGPKFA 539

  Fly   461 FIIFTEAINQFPGAQLWAVLFFLMLFTLGIDSQFGTLEGVVTSLVD-MKLFPNLPKEYIVGA--L 522
            |:.|.||::..|.:..|:.:|||||..:|:.|..|.::|::|.|.| ...|....|..|||.  |
Human   540 FLSFVEAMSFLPPSVFWSFIFFLMLLAMGLSSAIGIMQGIITPLQDTFSFFRKHTKLLIVGVFLL 604

  Fly   523 CFSCCTISMCFANGAGSYIFQLMDSFAGNFPLLIIALFECLSISYIYGVRRFSDDIEMMTGS--R 585
            .|.|   .:.|...:|||..:|:..:...||::::.:||.:::|:.||.|||..|:.::.|.  .
Human   605 MFVC---GLFFTRPSGSYFIRLLSDYWIVFPIIVVVVFETMAVSWAYGARRFLADLTILLGHPIS 666

  Fly   586 PNFYWMFCWKYLSPCAMVTILLASFYQLLTEGSSYPAWIGSKGATEGMEWPHWCIVVAFFLILSS 650
            |.|.|:  |.:|.|..::.|.:.....|..:..:|.:|..|........:|.|.:::  .:.|.:
Human   667 PIFGWL--WPHLCPVVLLIIFVTMMVHLCMKPITYMSWDSSTSKEVLRPYPPWALLL--MITLFA 727

  Fly   651 ILWIPIVAVLRLCGIKVV----EDSDPAWFPEAELREVHGIVPHEPTELE 696
            |:.:||.|....|.|..:    :..|........|...|.:.|.:..:.|
Human   728 IVILPIPAYFVYCRIHRIPFRPKSGDGPMTASTSLPLSHQLTPSKEVQKE 777

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10804	NP_001138150.1	SLC6sbd-B0AT-like	120..661	CDD:271364	175/591 (30%)
SLC6A16	XP_047294657.1	SLC6sbd_NTT5	162..732	CDD:271392	171/579 (30%)