Protein Alignment CG10804 and Slc6a15

DIOPT Version :10

• Sequence 1: NP_001138150.1
• Gene: CG10804 / 31317
• FlyBaseID: FBgn0029663
• Length: 726
• Species: Drosophila melanogaster
• Sequence 2: NP_758824.1
• Gene: Slc6a15 / 282712
• RGDID: 628664
• Length: 729
• Species: Rattus norvegicus
• Alignment Length: 679
• Identity: 280/679 - (41%)
• Similarity: 403/679 - (59%)
• Gaps: 77/679 - (11%)

  Fly    92 KAELVAIATASADQQDIVEGEKEGEERESWDSKIMFLLATIGYAVGLGNVWRFPYLAQKNGGGAF 156
            |:||:.......| .|..:|.:..:||.:|:||:.::||.:|::||||||||||||.|||||||:
  Rat    36 KSELIVDVQEEKD-TDAEDGSEVDDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAY 99

  Fly   157 LVPYFIMLCIQGIPIFYLELAIGQRLRKGAIGVWSQVSPYLGGIGISSAVVSYIVALYYNTIIAW 221
            |:||.|:|.:.|||:|:|||::|||:|:|:||||:.:||.|||||.:|.||.|.||||||.||.|
  Rat   100 LLPYLILLLVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGW 164

  Fly   222 CLIYLLHSFESPLPWADCPTRLYKNFTYDH-EPECVASSPTQFYWYRTTLQCSESVDMPENFNYH 285
            .|.|...||:.||||..||  |.||.::.: ||||..||.|.:||||..|..|.|:......|:.
  Rat   165 TLFYFSQSFQQPLPWDQCP--LVKNASHTYIEPECEKSSATTYYWYREALAISSSISESGGLNWK 227

  Fly   286 MAIALIVSWFLVYICMVQGITSSGKIVYMTAIFPYVVLIIFFFRGITLKGAADGVAHLFTPRWET 350
            |...|:.:|.:|.:.|::||.|||||:|.:::|||||||.|..|.:.|.|:.||:.|:|||:.|.
  Rat   228 MTGCLLAAWVMVCLAMIKGIQSSGKIMYFSSLFPYVVLICFLIRSLLLNGSIDGIRHMFTPKLEM 292

  Fly   351 LLDPVVWLEAGTQIFFSLGLAFGGLIAFSSYNPANNNCYRDAILVSLTNCGTSMFAGVVVFSVIG 415
            :|:|.||.||.||:||:|||.|||:|||||||..:|||:.||:|||..|..||:.|.:|||:|:|
  Rat   293 MLEPKVWREAATQVFFALGLGFGGVIAFSSYNKRDNNCHFDAVLVSFINFFTSVLATLVVFAVLG 357

  Fly   416 FKATATFDRCTEERNGLVAQ-NKTHN--------------------------------------- 440
            |||....::|..:.:.::.: .||.|
  Rat   358 FKANIVNEKCISQNSEMILKLLKTGNVSWDVIPRHINLSAVTAEDYHVVYDIIQKVKEEEFAVLH 422

  Fly   441 LPVCDLQTELANSASGTGLAFIIFTEAINQFPGAQLWAVLFFLMLFTLGIDSQFGTLEGVVTSLV 505
            |..|.::.||..:..|||||||.||||:..||.:..|:|:|||||..||:.|.|||:||::|.:|
  Rat   423 LKACQIEDELNKAVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMFGTIEGIITPVV 487

  Fly   506 DMKLFPNLPKEYIVGALCFSCCTISMCFANGAGSYIFQLMDSFAGNFPLLIIALFECLSISYIYG 570
            |..   .:.||.:....|.....|.:.|...:|:|...:.|.::...||||:.:.|.:::|::||
  Rat   488 DTF---KVRKEILTVICCLLAFCIGLMFVQRSGNYFVTMFDDYSATLPLLIVVILENIAVSFVYG 549

  Fly   571 VRRFSDDIEMMTGSRPNFYWMFCWKYLSPCAMVTILLASFYQLLTEGSSYPAWIGSKGATEGMEW 635
            :.:|.:|:..|.|..|:.|:.:.|||:||..:||:|:||...:......|.|||..|.:.|.:.:
  Rat   550 IDKFLEDLTDMLGFAPSKYYYYMWKYISPLMLVTLLIASIVNMGLSPPGYNAWIKEKASEEFLSY 614

  Fly   636 PHWCIVVAFFLILSSILWIPIVAVLRLCGIKVVEDSDPAWFPEAELREV---HGIVPHEPTELER 697
            |.|.:||.|.|::.:||.:|:|.|:|.|.:  ::||      ...|..|   .|.|..||.
  Rat   615 PMWGMVVCFSLMVLAILPVPVVFVIRRCNL--IDDS------SGNLASVTYKRGRVLKEPV---- 667

  Fly   698 SIFCFNMDGTEG----------MCCPKYG 716
                 |:||.:.          |..|.:|
  Rat   668 -----NLDGDDASLIHGKIPSEMSSPNFG 691

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10804	NP_001138150.1	SLC6sbd-B0AT-like	120..661	CDD:271364	256/581 (44%)
Slc6a15	NP_758824.1	SLC6sbd_SBAT1	61..640	CDD:212091	257/583 (44%)