Protein Alignment CG10804 and Slc6a6

DIOPT Version :10

• Sequence 1: NP_001138150.1
• Gene: CG10804 / 31317
• FlyBaseID: FBgn0029663
• Length: 726
• Species: Drosophila melanogaster
• Sequence 2: NP_033346.2
• Gene: Slc6a6 / 21366
• MGIID: 98488
• Length: 621
• Species: Mus musculus
• Alignment Length: 618
• Identity: 223/618 - (36%)
• Similarity: 322/618 - (52%)
• Gaps: 86/618 - (13%)

  Fly   110 EGEKEGE--ERESWDSKIMFLLATIGYAVGLGNVWRFPYLAQKNGGGAFLVPYFIMLCIQGIPIF 172
            |.|.:|:  :||.|.|||.|:|:..|..||||||||||||..||||||||:||||.|...|:|:|
Mouse    31 EDEADGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVF 95

  Fly   173 YLELAIGQRLRKGAIGVWSQVSPYLGGIGISSAVVSYIVALYYNTIIAWCLIYLLHSFESPLPWA 237
            :||:.|||...:|.|..|.::.|...|||.:|.|:..::.:||..|:||...||.|||:..||||
Mouse    96 FLEVIIGQYTSEGGITCWEKICPLFSGIGYASIVIVSLLNVYYIVILAWATYYLFHSFQKDLPWA 160

  Fly   238 DCPTRLYKNFTYDHEPECVA------------------SSPTQFYWYRTTLQCSESVDMPENFNY 284
            .|      |.:: :.|:|:.                  :||...:|.|..|..|..:|.|.:..:
Mouse   161 HC------NHSW-NTPQCMEDTLRRNESHWVSLSTANFTSPVIEFWERNVLSLSSGIDNPGSLKW 218

  Fly   285 HMAIALIVSWFLVYICMVQGITSSGKIVYMTAIFPYVVLIIFFFRGITLKGAADGVAHLFTPRWE 349
            .:|:.|::.|.:.:.|:.:|:.|:||:||.||.||:.:|::...||:||.||.:|:.....|...
Mouse   219 DLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLTLPGAGEGIKFYLYPDIS 283

  Fly   350 TLLDPVVWLEAGTQIFFSLGLAFGGLIAFSSYNPANNNCYRDAILVSLTNCGTSMFAGVVVFSVI 414
            .|.||.||::||||||||..:..|.:.:..|||....|.|||.:|:...|.|||..:|..:||::
Mouse   284 RLGDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDCMLLGCLNSGTSFVSGFAIFSIL 348

  Fly   415 GFKATATFDRCTEERNGLVAQNKTHNLPVCDLQTELANSASGTGLAFIIFTEAINQFPGAQLWAV 479
            ||.|                  :...:.:.|:      :.||.|||||.:.:|:...|....|::
Mouse   349 GFMA------------------QEQGVDIADV------AESGPGLAFIAYPKAVTMMPLPTFWSI 389

  Fly   480 LFFLMLFTLGIDSQFGTLEGVVTSLVDMKLFPNL-----PKEYIVGALCFSCCTISMCFANGAGS 539
            |||:||..||:||||..:||.:|||||  |:|:.     .:|..:..||.....:.:......|.
Mouse   390 LFFIMLLLLGLDSQFVEVEGQITSLVD--LYPSFLRKGYRREIFIAILCSISYLLGLTMVTEGGM 452

  Fly   540 YIFQLMDSFAGN-FPLLIIALFECLSISYIYGVRRFSDDIEMMTGSRPNFYWMFCWKYLSPCAMV 603
            |:|||.|.:|.: ..||.:|.|||..|::|||.....|.||.|.|.||..:..:.|..::|...|
Mouse   453 YVFQLFDYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITPALCV 517

  Fly   604 TILLASF--YQLLTEGSSYPAWIGSKGATEGMEWPHWCIVVAFFLILSSILWIPIVAVLRLCGIK 666
            ...:.|.  |..||....|             .:|.|.|.:.:.|.|||:|.||:|.|:.||
Mouse   518 GCFVFSLVKYVPLTYNKVY-------------RYPDWAIGLGWGLALSSMLCIPLVIVILLC--- 566

  Fly   667 VVEDSDPAWFPEAELREVHGIVPHEPTE--LER 697
              ....|     ..:|..:.|.|.||..  :||
Mouse   567 --RTEGP-----LRVRIKYLITPREPNRWAVER 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10804	NP_001138150.1	SLC6sbd-B0AT-like	120..661	CDD:271364	208/566 (37%)
Slc6a6	NP_033346.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..42		3/10 (30%)
		SLC5-6-like_sbd	41..582	CDD:444915	215/596 (36%)