Protein Alignment CG10804 and dat-1

DIOPT Version :9

• Sequence 1: NP_001138150.1
• Gene: CG10804 / 31317
• FlyBaseID: FBgn0029663
• Length: 726
• Species: Drosophila melanogaster
• Sequence 2: NP_499043.1
• Gene: dat-1 / 176304
• WormBaseID: WBGene00000934
• Length: 615
• Species: Caenorhabditis elegans
• Alignment Length: 587
• Identity: 220/587 - (37%)
• Similarity: 312/587 - (53%)
• Gaps: 79/587 - (13%)

  Fly   109 VEGEKEGEERESWDSKIMFLLATIGYAVGLGNVWRFPYLAQKNGGGAFLVPYFIMLCIQGIPIFY 173
            |..|.:...||.|..|:.|||:.:|:||.|||:||||||..|||||.||:||.||:.:.|:|:||
 Worm    31 VNTEPKDPAREQWSGKLDFLLSVVGFAVDLGNIWRFPYLCFKNGGGVFLIPYSIMVLLTGVPLFY 95

  Fly   174 LELAIGQRLRKGAIGVWSQVSPYLGGIGISSAVVSYIVALYYNTIIAWCLIYLLHSFESPLPWAD 238
            :||.:||..|||||..|.::.|...|||....:.::.|..:||.|:||.|.||..||...||||.
 Worm    96 MELCLGQYYRKGAITTWGRICPLFKGIGYCVILTAFYVDFFYNVILAWGLHYLYTSFSFNLPWAS 160

  Fly   239 C------PTRLYKNFTYDHEPECVAS---------SPTQFYWYRTTLQCSE----------SVDM 278
            |      |.....:::.|....|.::         |..:.|:|:..|...|          ||..
 Worm   161 CNNSYNSPACYEPHWSEDGTAMCRSANQSVSAEKISAAEEYFYKGFLGLHEANAPNSHVIRSVTD 225

  Fly   279 PENFNYHMAIALIVSWFLVYICMVQGITSSGKIVYMTAIFPYVVLIIFFFRGITLKGAADGVAHL 343
            ..|..:.:|::|.|.:.:.|..|.:||.:|||:|:.||:||||||.|.|.||:||.|..:|:.:.
 Worm   226 LGNVRWDIALSLFVVYLICYFSMWKGIHTSGKVVWFTALFPYVVLGILFIRGVTLPGWQNGIEYY 290

  Fly   344 FTPRWETLLDPVVWLEAGTQIFFSLGLAFGGLIAFSSYNPANNNCYRDAILVSLTNCGTSMFAGV 408
            ..|.:|.|..|.||.:|.||:|||||..||.|:|:||||..:||.|.||:..|..||.||..:|.
 Worm   291 LRPNFEMLKRPSVWQDAATQVFFSLGPGFGVLMAYSSYNDFHNNVYVDALFTSFINCATSFLSGF 355

  Fly   409 VVFSVIGFKATATFDRCTEERNG----LVAQNKTHNLPVCDLQTELANSASGTGLAFIIFTEAIN 469
            |:|||:|:.:      |   ::|    .|||                   .|.||.|:::.||::
 Worm   356 VIFSVLGYMS------C---KSGKPIEAVAQ-------------------EGPGLVFVVYPEALS 392

  Fly   470 QFPGAQLWAVLFFLMLFTLGIDSQFGTLEGVVTSLVDMKLFPNLPK--EYIVGALCFSCCTISMC 532
            ..|.|..|:|||||||.|||:||.||..|.::|.|.|.  ||.|.|  |..||.|......|.:.
 Worm   393 TMPYAPFWSVLFFLMLMTLGLDSSFGGSEAIITGLSDE--FPILKKNREVFVGCLFAFYMVIGIA 455

  Fly   533 FANGAGSYIFQLMDSFAGNFPLLIIALFECLSISYIYGVRRFSDDIEMMTGSRPNFYWMFCWKYL 597
            .....|..|.:.:..:...:.|||....|.:.|:||||:|:|..|::.|.|.||..||.|||...
 Worm   456 MCTEGGILIMEWLIIYGTTWGLLIAVFCEAMVIAYIYGLRQFVHDVKEMMGFRPGNYWKFCWSCA 520

  Fly   598 SPCAMVTILLASF--YQLLT-EGSSYPAWIGSKGATEGMEWPHWCIVVAFFLILSSILWIPIVAV 659
            :|..:::::.::|  ||.|| :..:||....               |:.....||...:||:|.:
 Worm   521 APFILLSMITSNFINYQALTYQDYTYPTAAN---------------VIGIIFALSGASFIPLVGI 570

  Fly   660 LR 661
            .:
 Worm   571 YK 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10804	NP_001138150.1	SLC6sbd-B0AT-like	120..661	CDD:271364	216/574 (38%)
dat-1	NP_499043.1	SLC6sbd_SERT-like_u1	40..591	CDD:271405	218/578 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810