Protein Alignment CG10804 and Slc6a13

DIOPT Version :10

• Sequence 1: NP_001138150.1
• Gene: CG10804 / 31317
• FlyBaseID: FBgn0029663
• Length: 726
• Species: Drosophila melanogaster
• Sequence 2: XP_006237280.2
• Gene: Slc6a13 / 171163
• RGDID: 620788
• Length: 608
• Species: Rattus norvegicus
• Alignment Length: 652
• Identity: 220/652 - (33%)
• Similarity: 325/652 - (49%)
• Gaps: 128/652 - (19%)

  Fly   112 EKEGE-ERESWDSKIMFLLATIGYAVGLGNVWRFPYLAQKNGGGAFLVPYFIMLCIQGIPIFYLE 175
            |::|. |||.|.:|:.|:|:..|..:|||||||||||..|||||||.:||.|.|...|||:|:||
  Rat    25 EEDGTLEREQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYLIFLFTCGIPVFFLE 89

  Fly   176 LAIGQRLRKGAIGVWSQVSPYL------GGIGISSAVVSYIVALYYNTIIAWCLIYLLHSFESPL 234
            .|:||...:|.|..|.::.|..      .|||.:|.::..::.:||..::||.|.||..||.:.|
  Rat    90 TALGQYTNQGGITAWRKICPIFEASVPSPGIGYASQMIVSLLNVYYIVVLAWALFYLFSSFTTDL 154

  Fly   235 PWADCPTRLYKNFTYDHE---PECV---------------ASSPTQFYWYRTTLQCSESVDMPEN 281
            ||..|          .||   ..||               |:||...:|.|..|:.|:.:....:
  Rat   155 PWGSC----------SHEWNTENCVEFQKTNNSLNVTSENATSPVIEFWERRVLKISDGIQHLGS 209

  Fly   282 FNYHMAIALIVSWFLVYICMVQGITSSGKIVYMTAIFPYVVLIIFFFRGITLKGAADGVAHLFTP 346
            ..:.:.:.|:::|.:.|.|:.:|:.|:||:||.||.|||::|::...||:||.|||.|:.....|
  Rat   210 LRWELVLCLLLAWIICYFCIWKGVKSTGKVVYFTATFPYLMLVVLLIRGVTLPGAAQGIQFYLYP 274

  Fly   347 RWETLLDPVVWLEAGTQIFFSLGLAFGGLIAFSSYNPANNNCYRDAILVSLTNCGTSMFAGVVVF 411
            ....|.||.||::||||||||..:..|.|.|..|||..:||||||.:.:.:.|..||..||..:|
  Rat   275 NITRLWDPQVWMDAGTQIFFSFAICLGCLTALGSYNKYHNNCYRDCVALCILNSSTSFVAGFAIF 339

  Fly   412 SVIGFKATATFDRCTEERNGLVAQNKTHNLPVCDLQTELANSASGTGLAFIIFTEAINQFPGAQL 476
            |::||                  .::...:|:.::      :.||.|||||.:..|:...|.:.|
  Rat   340 SILGF------------------MSQEQGVPISEV------AESGPGLAFIAYPRAVVMLPFSPL 380

  Fly   477 WAVLFFLMLFTLGIDSQFGTLEGVVTSLVDMKLFPNLPKE--------YIVGALCFSCCTISMCF 533
            ||..||.|:..||:||||..:|.:||:||||  :|.:.::        .||..:.|   .|.:..
  Rat   381 WACCFFFMVVLLGLDSQFVCVESLVTALVDM--YPRVFRKKNRREILILIVSVVSF---FIGLIM 440

  Fly   534 ANGAGSYIFQLMDSFAGN-FPLLIIALFECLSISYIYGVRRFSDDIEMMTGSRPNFYW---MFCW 594
            ....|.|:|||.|.:|.: ..||.:|:||.|.::::||..||.|:||.|.|.:|   |   .:||
  Rat   441 LTEGGMYVFQLFDYYAASGMCLLFVAIFESLCVAWVYGASRFYDNIEDMIGYKP---WPLIKYCW 502

  Fly   595 KYLSPCAMVTILLASF--YQLLTEGSSYPAWIGSKGATEGMEWPHWCIVVAFFLILSSILWIPIV 657
            .:.:|...:...|.|.  |..||....|             .:|.|...:.:.|.|||::.||..
  Rat   503 LFFTPAVCLATFLFSLIKYTPLTYNKKY-------------TYPWWGDALGWLLALSSMVCIPAW 554

  Fly   658 AVLRLCGIKVVEDSDPAWFPEAELREVHGIVPHEPTELERSIFCFNMDGTEGMCCPKYGLPEKSL 722
            ::.:|..:|            ..|||          .|.:            :.||...||:||.
  Rat   555 SIYKLRTLK------------GPLRE----------RLRQ------------LVCPAEDLPQKSQ 585

  Fly   723 EE 724
            .|
  Rat   586 PE 587

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10804	NP_001138150.1	SLC6sbd-B0AT-like	120..661	CDD:271364	202/578 (35%)
Slc6a13	XP_006237280.2	SLC5-6-like_sbd	32..581	CDD:444915	212/637 (33%)